C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: F-box and WD-40 domain protein 7
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000107675 Fbxw7-005 ENSMUSG00000028086 10090 + 3:84925480-84979197 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBreastColonHeartKidneyLiverLungMuscleOvaryENSMUST00000107675
Transcript ID Adipose Breast Colon Heart Kidney Liver Lung Muscle Ovary
ENSMUST00000107675 0.744±0.23 1.216±0.57 1.961±0.50 11.165±1.62 0.956±0.33 0.793±0.35 2.141±0.29 4.691±0.68 3.096±0.61

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00064N CIL_00064N_0002 CGP 3:84444035-85887516
CIL_0004PH CIL_0004PH_0002 CGP 3:84496093-85887516
CIL_0008CH CIL_0008CH_0002 VISTA 3:84637097-85239573

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001570 IMP vasculogenesis
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 TAS nucleus
GO:0005737 TAS cytoplasm
GO:0005783 IDA endoplasmic reticulum
GO:0005794 IDA Golgi apparatus
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0007219 IDA Notch signaling pathway
GO:0016567 ISA protein ubiquitination
GO:0030324 IMP lung development
GO:0031146 IBA SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000086512 FBXW7-201 protein_coding Danio_rerio 0 1064
ENSDART00000148076 FBXW7-001 protein_coding Danio_rerio 0 1064
ENST00000263981 FBXW7-005 protein_coding Homo_sapiens 0 2403
ENST00000281708 FBXW7-001 protein_coding Homo_sapiens 0 2403
ENST00000296555 FBXW7-003 protein_coding Homo_sapiens 0 2728
ENST00000393956 FBXW7-007 protein_coding Homo_sapiens 0 2276
ENST00000603548 FBXW7-002 protein_coding Homo_sapiens 0 2403
ENST00000603821 FBXW7-008 retained_intron Homo_sapiens 0 553
ENST00000603841 FBXW7-012 protein_coding Homo_sapiens 0 2392
ENST00000604069 FBXW7-010 retained_intron Homo_sapiens 0 808
ENST00000604316 FBXW7-011 retained_intron Homo_sapiens 0 741
ENST00000604822 FBXW7-009 retained_intron Homo_sapiens 0 300

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