C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: nuclear receptor subfamily 4, group A, member 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000112629 Nr4a2-001 ENSMUSG00000026826 10090 - 2:57106830-57124003 protein_coding

Mus musculus EnsemblGRCm38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000112629
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000112629 0.479±0.24 1.122±0.34 0.313±0.06 1.102±0.00 0.317±0.18 0.484±0.15 0.238±0.10 0.106±0.03 0.155±0.06 0.352±0.10 0.144±0.05 0.615±0.16 0.121±0.04 0.245±0.03

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000758 CIL_000758_0002 CGP 2:55435970-57124003
CIL_0007NB CIL_0007NB_0002 UCNEbase 2:56227555-57879432
CIL_0008JL CIL_0008JL_0002 VISTA 2:56616091-57216889
CIL_000759 CIL_000759_0002 CGP 2:57106830-57370719

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000977 IMP RNA polymerase II regulatory region sequence-specific DNA binding
GO:0000979 IDA RNA polymerase II core promoter sequence-specific DNA binding
GO:0001228 IDA RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001666 IMP response to hypoxia
GO:0001764 IMP neuron migration
GO:0001975 IMP response to amphetamine
GO:0003677 IDA DNA binding
GO:0003707 IEA steroid hormone receptor activity
GO:0004879 TAS ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0006351 IEA:IDA transcription, DNA-templated
GO:0006355 IMP regulation of transcription, DNA-templated
GO:0007399 IMP nervous system development
GO:0008270 IEA zinc ion binding
GO:0008344 IMP adult locomotory behavior
GO:0009791 IMP post-embryonic development
GO:0010035 ISO response to inorganic substance
GO:0010467 IMP gene expression
GO:0010468 IMP regulation of gene expression
GO:0016265 IMP death
GO:0017085 ISO response to insecticide
GO:0021952 IMP central nervous system projection neuron axonogenesis
GO:0021953 IMP central nervous system neuron differentiation
GO:0021986 IMP habenula development
GO:0030182 IMP neuron differentiation
GO:0030522 IEA intracellular receptor signaling pathway
GO:0031668 ISO cellular response to extracellular stimulus
GO:0034599 IMP cellular response to oxidative stress
GO:0042053 IDA regulation of dopamine metabolic process
GO:0042416 IMP dopamine biosynthetic process
GO:0042417 IMP dopamine metabolic process
GO:0042551 IMP neuron maturation
GO:0043085 IMP positive regulation of catalytic activity
GO:0043401 IEA steroid hormone mediated signaling pathway
GO:0043524 IMP negative regulation of neuron apoptotic process
GO:0043565 ISO sequence-specific DNA binding
GO:0043576 IMP regulation of respiratory gaseous exchange
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046982 IPI protein heterodimerization activity
GO:0051866 IMP general adaptation syndrome
GO:0071542 IDA dopaminergic neuron differentiation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000339562 NR4A2-001 protein_coding Homo_sapiens 0 4547
ENST00000406048 NR4A2-007 protein_coding Homo_sapiens 0 379
ENST00000409108 NR4A2-009 protein_coding Homo_sapiens 0 2080
ENST00000409572 NR4A2-010 protein_coding Homo_sapiens 0 3555
ENST00000417764 NR4A2-011 nonsense_mediated_decay Homo_sapiens 0 1677
ENST00000417972 NR4A2-006 nonsense_mediated_decay Homo_sapiens 0 1677
ENST00000421709 NR4A2-004 protein_coding Homo_sapiens 0 510
ENST00000424077 NR4A2-005 protein_coding Homo_sapiens 0 1206
ENST00000426264 NR4A2-003 protein_coding Homo_sapiens 0 3090
ENST00000429376 NR4A2-008 protein_coding Homo_sapiens 0 1709

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