C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: E2F transcription factor 8
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000119223 E2f8-001 ENSMUSG00000046179 10090 - 7:48866429-48881596 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000119223
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000119223 0.192±0.14 0.124±0.03 0.119±0.06 0.461±0.32 0.172±0.08 1.083±0.14 0.133±0.02 0.065±0.01 4.477±2.80 0.142±0.05 0.033±0.02 0.989±0.70 19.709±18.90 1.801±0.50

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008RI CIL_0008RI_0002 VISTA 7:48524185-49126415
CIL_0008YB CIL_0008YB_0002 VISTA 7:48559718-49163012
CIL_0007HT CIL_0007HT_0003 CGP 7:48830398-48881596
CIL_0004AV CIL_0004AV_0003 CGP 7:48866429-49610090

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IMP negative regulation of transcription from RNA polymerase II promoter
GO:0001890 IMP placenta development
GO:0002040 IMP sprouting angiogenesis
GO:0003677 IDA DNA binding
GO:0003700 IMP sequence-specific DNA binding transcription factor activity
GO:0003714 IMP transcription corepressor activity
GO:0005634 IDA nucleus
GO:0005667 IEA transcription factor complex
GO:0006351 IEA transcription, DNA-templated
GO:0008283 IDA cell proliferation
GO:0032466 IMP negative regulation of cytokinesis
GO:0032877 IMP positive regulation of DNA endoreduplication
GO:0033301 IMP cell cycle comprising mitosis without cytokinesis
GO:0042802 IPI identical protein binding
GO:0042803 IPI protein homodimerization activity
GO:0060707 IMP trophoblast giant cell differentiation
GO:0060718 IMP chorionic trophoblast cell differentiation
GO:0070365 IMP hepatocyte differentiation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000250024 E2F8-002 protein_coding Homo_sapiens 0 2320
ENST00000527884 E2F8-001 protein_coding Homo_sapiens 0 2582
ENST00000529188 E2F8-005 processed_transcript Homo_sapiens 0 191
ENST00000620009 E2F8-201 protein_coding Homo_sapiens 0 2595

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