C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: E2F transcription factor 8
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000620009 E2F8-201 ENSG00000129173 9606 - 11:19224066-19241620 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainBreastKidneyLungENST00000620009
Transcript ID Adipose Brain Breast Kidney Lung
ENST00000620009 0.055±0.00 0.006±0.00 0.062±0.00 0.012±0.00 0.028±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008RI CIL_0008RI_0001 VISTA 11:18872537-19474989
CIL_0008YB CIL_0008YB_0001 VISTA 11:18916805-19520451
CIL_0007HT CIL_0007HT_0002 CGP 11:19182030-19241620
CIL_0004AV CIL_0004AV_0002 CGP 11:19224063-20121598

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 ISS negative regulation of transcription from RNA polymerase II promoter
GO:0000978 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001047 IDA core promoter binding
GO:0001078 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0001890 ISS placenta development
GO:0002040 IMP sprouting angiogenesis
GO:0003677 IEA DNA binding
GO:0003700 IMP:IEA sequence-specific DNA binding transcription factor activity
GO:0003714 ISS transcription corepressor activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005667 IEA transcription factor complex
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0008283 IEA cell proliferation
GO:0032466 ISS negative regulation of cytokinesis
GO:0032877 ISS positive regulation of DNA endoreduplication
GO:0033301 ISS cell cycle comprising mitosis without cytokinesis
GO:0042802 IEA identical protein binding
GO:0042803 IEA protein homodimerization activity
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0060707 ISS trophoblast giant cell differentiation
GO:0060718 ISS chorionic trophoblast cell differentiation
GO:0070365 ISS hepatocyte differentiation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000119223 E2f8-001 protein_coding Mus_musculus 0 2595
ENSMUST00000058745 E2f8-002 protein_coding Mus_musculus 0 2582
ENSMUST00000151139 E2f8-004 retained_intron Mus_musculus 0 545

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