C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: integrin beta 1 (fibronectin receptor beta)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000124826 Itgb1-002 ENSMUSG00000025809 10090 + 8:128685757-128732617 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonKidneyLiverLungOvaryPlacentaTestisENSMUST00000124826
Transcript ID Adipose Adrenal Brain Breast Colon Kidney Liver Lung Ovary Placenta Testis
ENSMUST00000124826 29.195±11.10 20.460±2.36 3.657±0.00 13.931±3.87 25.689±9.34 11.808±3.57 5.177±0.98 45.477±6.46 30.884±11.41 36.196±16.77 3.133±2.55

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000CP CIL_0000CP_0002 CGP 8:128359073-128733200

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000082 IMP G1/S transition of mitotic cell cycle
GO:0001701 IMP in utero embryonic development
GO:0001708 IMP cell fate specification
GO:0002042 IMP cell migration involved in sprouting angiogenesis
GO:0004872 IEA receptor activity
GO:0005178 IPI integrin binding
GO:0005515 IPI protein binding
GO:0005886 IDA plasma membrane
GO:0007160 IGI cell-matrix adhesion
GO:0007229 IEA integrin-mediated signaling pathway
GO:0008284 IMP positive regulation of cell proliferation
GO:0008354 IMP germ cell migration
GO:0008542 IGI visual learning
GO:0009897 IDA external side of plasma membrane
GO:0009986 ISO cell surface
GO:0014704 IDA intercalated disc
GO:0016477 IMP cell migration
GO:0021943 IMP formation of radial glial scaffolds
GO:0031175 IMP neuron projection development
GO:0031594 IDA neuromuscular junction
GO:0034677 IPI integrin alpha7-beta1 complex
GO:0035024 IGI negative regulation of Rho protein signal transduction
GO:0042383 IDA sarcolemma
GO:0043197 IDA dendritic spine
GO:0043235 ISO receptor complex
GO:0043236 IDA laminin binding
GO:0045202 IDA synapse
GO:0045214 IMP sarcomere organization
GO:0045596 IMP negative regulation of cell differentiation
GO:0048675 IGI axon extension
GO:0048738 IMP cardiac muscle tissue development
GO:0048813 IGI dendrite morphogenesis
GO:0051726 IMP regulation of cell cycle
GO:0055007 IMP cardiac muscle cell differentiation
GO:0097060 IDA synaptic membrane

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000302278 ITGB1-001 protein_coding Homo_sapiens 0 2599
ENST00000396033 ITGB1-201 protein_coding Homo_sapiens 0 2599
ENST00000414670 ITGB1-002 protein_coding Homo_sapiens 1.99965e-42 176
ENST00000417122 ITGB1-003 protein_coding Homo_sapiens 5.99756e-43 178
ENST00000423113 ITGB1-202 protein_coding Homo_sapiens 0 2311
ENST00000437302 ITGB1-006 protein_coding Homo_sapiens 2.94273e-44 182
ENST00000464001 ITGB1-008 retained_intron Homo_sapiens 1e-31 139
ENST00000472147 ITGB1-013 protein_coding Homo_sapiens 5e-29 132
ENST00000474568 ITGB1-004 protein_coding Homo_sapiens 6e-29 132
ENST00000475184 ITGB1-012 protein_coding Homo_sapiens 2.00386e-43 180
ENST00000480226 ITGB1-009 protein_coding Homo_sapiens 5.99756e-43 178
ENST00000484088 ITGB1-011 processed_transcript Homo_sapiens 0 189
ENST00000488427 ITGB1-005 protein_coding Homo_sapiens 0 311
ENST00000488494 ITGB1-010 protein_coding Homo_sapiens 0 189
ENST00000493758 ITGB1-007 protein_coding Homo_sapiens 2e-30 135
ENST00000494395 ITGB1-014 nonsense_mediated_decay Homo_sapiens 0 381
ENST00000528877 ITGB1-015 protein_coding Homo_sapiens 2.8026e-45 185
ENST00000534049 ITGB1-016 protein_coding Homo_sapiens 5.99756e-43 178
ENST00000596032 ITGB1P1-001 processed_pseudogene Homo_sapiens 0 710

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