C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: ATP-binding cassette, sub-family A (ABC1), member 7
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000132517 Abca7-001 ENSMUSG00000035722 10090 + 10:79996494-80015572 protein_coding

Mus musculus EnsemblGRCm38

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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000132517
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000132517 3.361±0.59 2.911±0.62 1.498±0.46 1.763±0.00 5.423±2.17 8.563±2.90 1.667±0.48 2.266±0.72 2.445±2.42 4.820±1.85 1.605±0.19 2.757±1.11 1.483±0.54 0.611±0.04

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008XG CIL_0008XG_0002 VISTA 10:79539861-80142369
CIL_0000I2 CIL_0000I2_0002 CGP 10:79988584-80015572
CIL_0000HU CIL_0000HU_0002 CGP 10:79996494-80031472

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001891 IDA phagocytic cup
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005548 IDA phospholipid transporter activity
GO:0005622 IDA intracellular
GO:0005737 IEA cytoplasm
GO:0005768 IEA endosome
GO:0005794 IEA Golgi apparatus
GO:0005886 ISS plasma membrane
GO:0006200 IEA ATP catabolic process
GO:0006909 IEA phagocytosis
GO:0007613 IMP memory
GO:0009986 IDA cell surface
GO:0010875 IDA positive regulation of cholesterol efflux
GO:0016021 IEA integral component of membrane
GO:0016324 IDA apical plasma membrane
GO:0016887 IEA ATPase activity
GO:0017121 ISS phospholipid scrambling
GO:0018149 IDA peptide cross-linking
GO:0032587 IDA ruffle membrane
GO:0032780 ISS negative regulation of ATPase activity
GO:0032781 ISS positive regulation of ATPase activity
GO:0033344 ISS cholesterol efflux
GO:0033700 IDA phospholipid efflux
GO:0034188 IDA apolipoprotein A-I receptor activity
GO:0034380 ISS high-density lipoprotein particle assembly
GO:0034504 IDA protein localization to nucleus
GO:0038027 IDA apolipoprotein A-I-mediated signaling pathway
GO:0042985 IDA negative regulation of amyloid precursor protein biosynthetic process
GO:0050766 IMP positive regulation of phagocytosis
GO:0070374 IMP positive regulation of ERK1 and ERK2 cascade
GO:1900223 IMP positive regulation of beta-amyloid clearance
GO:1901076 IMP positive regulation of engulfment of apoptotic cell
GO:1902430 IDA negative regulation of beta-amyloid formation
GO:1902995 IDA positive regulation of phospholipid efflux

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000136772 abca4a-002 protein_coding Danio_rerio 0.000000004 69
ENST00000263094 ABCA7-201 protein_coding Homo_sapiens 0 1984
ENST00000265662 ABCA2-201 protein_coding Homo_sapiens 7e-38 165
ENST00000341511 ABCA2-002 protein_coding Homo_sapiens 7e-38 165
ENST00000371605 ABCA2-202 protein_coding Homo_sapiens 7e-38 165
ENST00000433129 ABCA7-001 protein_coding Homo_sapiens 0 1984
ENST00000435683 ABCA7-002 protein_coding Homo_sapiens 0 1984
ENST00000437791 ABCA2-006 processed_transcript Homo_sapiens 3e-37 159
ENST00000459850 ABCA2-013 retained_intron Homo_sapiens 7e-38 165
ENST00000463603 ABCA2-008 retained_intron Homo_sapiens 5e-39 165
ENST00000479446 ABCA2-009 nonsense_mediated_decay Homo_sapiens 5e-38 165
ENST00000487109 ABCA2-016 nonsense_mediated_decay Homo_sapiens 6e-38 165
ENST00000532194 ABCA7-014 retained_intron Homo_sapiens 0 656
ENST00000614293 ABCA2-203 protein_coding Homo_sapiens 7e-38 165

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