C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: slit homolog 2 (Drosophila)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000174421 Slit2-006 ENSMUSG00000031558 10090 + 5:47984811-48304522 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; LiverENSMUST00000174421
Transcript ID Liver
ENSMUST00000174421 0.004±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002OP CIL_0002OP_0002 CGP 5:45697181-48306282
CIL_0002OO CIL_0002OO_0002 CGP 5:47983155-48388756

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001656 IMP metanephros development
GO:0001657 IEA ureteric bud development
GO:0001701 IMP in utero embryonic development
GO:0001933 IEA negative regulation of protein phosphorylation
GO:0002042 IEA cell migration involved in sprouting angiogenesis
GO:0002689 IEA negative regulation of leukocyte chemotaxis
GO:0005095 IEA GTPase inhibitor activity
GO:0005102 TAS receptor binding
GO:0005509 IEA calcium ion binding
GO:0005515 IPI protein binding
GO:0005615 IDA extracellular space
GO:0005737 IEA cytoplasm
GO:0007409 IDA axonogenesis
GO:0007411 IGI axon guidance
GO:0008045 IEA motor neuron axon guidance
GO:0008201 IEA heparin binding
GO:0008285 IGI negative regulation of cell proliferation
GO:0009986 IEA cell surface
GO:0010593 IEA negative regulation of lamellipodium assembly
GO:0010596 IEA negative regulation of endothelial cell migration
GO:0010629 IGI negative regulation of gene expression
GO:0014912 IEA negative regulation of smooth muscle cell migration
GO:0016337 IGI single organismal cell-cell adhesion
GO:0021772 IGI olfactory bulb development
GO:0021836 IEA chemorepulsion involved in postnatal olfactory bulb interneuron migration
GO:0021972 IEA corticospinal neuron axon guidance through spinal cord
GO:0022029 IGI telencephalon cell migration
GO:0030308 IEA negative regulation of cell growth
GO:0030336 IEA negative regulation of cell migration
GO:0030517 IDA negative regulation of axon extension
GO:0030837 IEA negative regulation of actin filament polymerization
GO:0031290 IGI retinal ganglion cell axon guidance
GO:0032870 IEA cellular response to hormone stimulus
GO:0033563 IGI dorsal/ventral axon guidance
GO:0042802 IEA identical protein binding
GO:0042803 IEA protein homodimerization activity
GO:0043065 IEA positive regulation of apoptotic process
GO:0043086 IEA negative regulation of catalytic activity
GO:0043116 IEA negative regulation of vascular permeability
GO:0043237 IEA laminin-1 binding
GO:0043394 IEA proteoglycan binding
GO:0045499 IMP chemorepellent activity
GO:0048495 IEA Roundabout binding
GO:0048754 IEA branching morphogenesis of an epithelial tube
GO:0048812 IGI neuron projection morphogenesis
GO:0048846 IEA axon extension involved in axon guidance
GO:0050919 IMP negative chemotaxis
GO:0050929 IEA induction of negative chemotaxis
GO:0051058 IEA negative regulation of small GTPase mediated signal transduction
GO:0051414 IEA response to cortisol
GO:0060603 IGI mammary gland duct morphogenesis
GO:0060763 IMP mammary duct terminal end bud growth
GO:0061364 IEA apoptotic process involved in luteolysis
GO:0070062 IEA extracellular vesicular exosome
GO:0070100 IEA negative regulation of chemokine-mediated signaling pathway
GO:0071504 IEA cellular response to heparin
GO:0071672 IEA negative regulation of smooth muscle cell chemotaxis
GO:0071676 IEA negative regulation of mononuclear cell migration
GO:0090024 IEA negative regulation of neutrophil chemotaxis
GO:0090260 IEA negative regulation of retinal ganglion cell axon guidance
GO:0090288 IEA negative regulation of cellular response to growth factor stimulus

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000273739 SLIT2-004 protein_coding Homo_sapiens 0 6139
ENST00000503823 SLIT2-002 protein_coding Homo_sapiens 0 5600
ENST00000503837 SLIT2-003 protein_coding Homo_sapiens 0 5740
ENST00000504154 SLIT2-001 protein_coding Homo_sapiens 0 5882
ENST00000508541 SLIT2-005 retained_intron Homo_sapiens 0 1016
ENST00000508824 SLIT2-006 protein_coding Homo_sapiens 0 468
ENST00000509394 SLIT2-009 processed_transcript Homo_sapiens 0 551
ENST00000509941 SLIT2-010 protein_coding Homo_sapiens 0 603
ENST00000511508 SLIT2-012 protein_coding Homo_sapiens 0 630
ENST00000512993 SLIT2-011 protein_coding Homo_sapiens 0 283
ENST00000622093 SLIT2-201 protein_coding Homo_sapiens 0 5766

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