C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: sine oculis-related homeobox 4
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000175693 Six4-002 ENSMUSG00000034460 10090 - 12:73103441-73113456 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonKidneyLiverLungOvaryPlacentaTestisENSMUST00000175693
Transcript ID Adipose Adrenal Brain Breast Colon Kidney Liver Lung Ovary Placenta Testis
ENSMUST00000175693 0.106±0.07 0.103±0.04 0.044±0.02 0.168±0.00 0.079±0.04 0.072±0.00 0.007±0.00 0.265±0.04 0.420±0.19 0.023±0.01 0.031±0.01

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008MW CIL_0008MW_0002 VISTA 12:72750612-73352572
CIL_0006SM CIL_0006SM_0003 CGP 12:73040015-73113456
CIL_0006SL CIL_0006SL_0003 CGP 12:73099609-73273988

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003677 IDA DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0005634 IC nucleus
GO:0007519 IGI skeletal muscle tissue development
GO:0008582 IGI regulation of synaptic growth at neuromuscular junction
GO:0010468 IGI regulation of gene expression
GO:0032880 IGI regulation of protein localization
GO:0042472 IGI inner ear morphogenesis
GO:0043565 IDA sequence-specific DNA binding
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0048538 IGI thymus development
GO:0048701 IGI embryonic cranial skeleton morphogenesis
GO:0048704 IGI embryonic skeletal system morphogenesis
GO:0048856 IGI anatomical structure development
GO:0051451 IGI myoblast migration

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000216513 SIX4-001 protein_coding Homo_sapiens 0 2089
ENST00000303077 SIX2-001 protein_coding Homo_sapiens 0 239
ENST00000317578 SIX5-001 protein_coding Homo_sapiens 0 233
ENST00000554079 SIX4-002 processed_transcript Homo_sapiens 0 904
ENST00000556952 SIX4-004 protein_coding Homo_sapiens 0 2185
ENST00000560160 SIX5-003 protein_coding Homo_sapiens 0 233

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