C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: leucine proline-enriched proteoglycan (leprecan) 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000236040 LEPRE1-002 ENSG00000117385 9606 - 1:42746375-42767012 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartLungOvaryTestisENST00000236040
Transcript ID Brain Heart Lung Ovary Testis
ENST00000236040 1.300±0.00 0.463±0.00 4.562±0.00 3.021±1.01 3.316±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008PM CIL_0008PM_0001 VISTA 1:42456139-43057783
CIL_0005B1 CIL_0005B1_0002 CGP 1:42733093-42767084
CIL_0005B2 CIL_0005B2_0002 CGP 1:42746335-42794493

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003674 ND molecular_function
GO:0005506 IEA iron ion binding
GO:0005518 ISS collagen binding
GO:0005578 IEA proteinaceous extracellular matrix
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005783 IDA endoplasmic reticulum
GO:0005788 TAS endoplasmic reticulum lumen
GO:0006457 IMP protein folding
GO:0008285 NAS negative regulation of cell proliferation
GO:0016020 IDA membrane
GO:0016049 IEA cell growth
GO:0016491 IEA oxidoreductase activity
GO:0016705 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0016706 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0018126 IMP protein hydroxylation
GO:0019511 IEA peptidyl-proline hydroxylation
GO:0019797 ISS procollagen-proline 3-dioxygenase activity
GO:0030198 TAS extracellular matrix organization
GO:0030199 IEA collagen fibril organization
GO:0030278 IEA regulation of ossification
GO:0031418 IEA L-ascorbic acid binding
GO:0032403 ISS protein complex binding
GO:0032963 ISS collagen metabolic process
GO:0032991 ISS macromolecular complex
GO:0050708 IMP regulation of protein secretion
GO:0050821 IMP protein stabilization
GO:0055114 IEA oxidation-reduction process
GO:0060348 IMP bone development
GO:0061077 ISS chaperone-mediated protein folding
GO:0070062 IDA extracellular vesicular exosome
GO:1901874 IMP negative regulation of post-translational protein modification

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000102662 Lepre1-003 protein_coding Mus_musculus 0 2383
ENSMUST00000121111 Lepre1-001 protein_coding Mus_musculus 0 2383
ENSMUST00000030393 Lepre1-012 protein_coding Mus_musculus 0 2296
ENSMUST00000081606 Lepre1-007 protein_coding Mus_musculus 0 2030
ENSMUST00000153940 Lepre1-002 processed_transcript Mus_musculus 0 1825
ENSMUST00000136278 Lepre1-004 nonsense_mediated_decay Mus_musculus 0 1142
ENSMUST00000131875 Lepre1-005 processed_transcript Mus_musculus 0 767
ENSMUST00000123963 Lepre1-011 processed_transcript Mus_musculus 0 401
ENSMUST00000126056 Lepre1-006 processed_transcript Mus_musculus 0 401
ENSMUST00000127087 Lepre1-009 retained_intron Mus_musculus 0 307
ENSMUST00000142361 Lepre1-010 processed_transcript Mus_musculus 3.00018e-42 178

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