C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000022620 Chrna2-001 ENSMUSG00000022041 10090 + 14:66140960-66152948 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000022620
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000022620 0.175±0.14 0.278±0.19 0.082±0.01 0.106±0.00 0.483±0.09 0.069±0.03 0.370±0.12 0.104±0.03 0.708±0.64 0.063±0.02 0.166±0.07 1.379±0.75 0.140±0.06 0.623±0.28

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000P3 CIL_0000P3_0002 CGP 14:66084377-66152948
CIL_0000OS CIL_0000OS_0003 CGP 14:66140960-66281052

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004889 IEA acetylcholine-activated cation-selective channel activity
GO:0005892 IEA acetylcholine-gated channel complex
GO:0006812 IEA cation transport
GO:0007165 IEA signal transduction
GO:0008144 IEA drug binding
GO:0015464 IEA acetylcholine receptor activity
GO:0030054 IEA cell junction
GO:0042166 IEA acetylcholine binding
GO:0045211 IEA postsynaptic membrane
GO:0051291 IEA protein heterooligomerization
GO:0071944 IDA cell periphery
GO:0098655 IEA cation transmembrane transport

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000033947 chrna2a-001 protein_coding Danio_rerio 0 688
ENSDART00000079613 chrna2b-201 protein_coding Danio_rerio 0 688
ENSDART00000136317 chrna2b-001 protein_coding Danio_rerio 0 688
ENST00000240132 CHRNA2-004 protein_coding Homo_sapiens 0 1399
ENST00000370263 CHRNA4-001 protein_coding Homo_sapiens 0 869
ENST00000407991 CHRNA2-201 protein_coding Homo_sapiens 0 1528
ENST00000463705 CHRNA4-002 processed_transcript Homo_sapiens 0 693
ENST00000467563 CHRNA4-004 processed_transcript Homo_sapiens 0 802
ENST00000498043 CHRNA4-007 nonsense_mediated_decay Homo_sapiens 0 693
ENST00000520933 CHRNA2-001 protein_coding Homo_sapiens 0 1528
ENST00000522008 CHRNA2-012 retained_intron Homo_sapiens 0 710
ENST00000523529 CHRNA2-006 retained_intron Homo_sapiens 0 1528
ENST00000523695 CHRNA2-005 nonsense_mediated_decay Homo_sapiens 0 994
ENST00000615287 CHRNA4-201 protein_coding Homo_sapiens 0 693

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