C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info

Description: cholinergic receptor, nicotinic, alpha polypeptide 2a (neuronal)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSDART00000033947 chrna2a-001 ENSDARG00000006602 7955 + 17:5843715-5865654 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyENSDART00000033947
Transcript ID Brain Heart Kidney
ENSDART00000033947 1.312±0.18 0.053±0.03 0.080±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000P3 CIL_0000P3_0001 CGP 17:5780077-5865654
CIL_0000OS CIL_0000OS_0001 CGP 17:5843715-5966650

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004889 IEA acetylcholine-activated cation-selective channel activity
GO:0005216 IEA ion channel activity
GO:0005230 IEA extracellular ligand-gated ion channel activity
GO:0005886 IEA plasma membrane
GO:0005892 IDA acetylcholine-gated channel complex
GO:0006810 IEA transport
GO:0006811 IEA ion transport
GO:0015464 IDA acetylcholine receptor activity
GO:0016020 IEA membrane
GO:0016021 IEA integral to membrane
GO:0030054 IEA cell junction
GO:0045202 IEA synapse
GO:0045211 IEA postsynaptic membrane

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000022620 Chrna2-001 protein_coding Mus_musculus 0 688
ENSMUST00000029562 Chrnb2-201 protein_coding Mus_musculus 3e-30 139
ENSMUST00000067120 Chrna4-001 protein_coding Mus_musculus 0 492
ENSMUST00000108851 Chrna4-002 protein_coding Mus_musculus 0 492
ENSMUST00000135766 Chrna4-004 nonsense_mediated_decay Mus_musculus 6e-24 115
ENST00000240132 CHRNA2-004 protein_coding Homo_sapiens 0 719
ENST00000368476 CHRNB2-001 protein_coding Homo_sapiens 8e-26 124
ENST00000370263 CHRNA4-001 protein_coding Homo_sapiens 0 623
ENST00000407991 CHRNA2-201 protein_coding Homo_sapiens 0 752
ENST00000463705 CHRNA4-002 processed_transcript Homo_sapiens 0 497
ENST00000467563 CHRNA4-004 processed_transcript Homo_sapiens 0 556
ENST00000498043 CHRNA4-007 nonsense_mediated_decay Homo_sapiens 0 497
ENST00000520933 CHRNA2-001 protein_coding Homo_sapiens 0 752
ENST00000522008 CHRNA2-012 retained_intron Homo_sapiens 0 488
ENST00000523529 CHRNA2-006 retained_intron Homo_sapiens 0 752
ENST00000523695 CHRNA2-005 nonsense_mediated_decay Homo_sapiens 0 436
ENST00000615287 CHRNA4-201 protein_coding Homo_sapiens 0 497

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