C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: potassium voltage-gated channel, shaker-related subfamily, member 5
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000252321 KCNA5-001 ENSG00000130037 9606 + 12:5043989-5046788 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000252321
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000252321 0.275±0.00 0.820±0.00 0.168±0.00 1.424±0.69 0.996±0.00 4.006±3.87 1.602±0.93 0.656±0.63 0.388±0.37 1.441±1.33 0.598±0.02 0.729±0.51 2.969±3.02 1.520±1.31

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001666 IEA response to hypoxia
GO:0005102 IEA receptor binding
GO:0005216 IEA ion channel activity
GO:0005249 IEA voltage-gated potassium channel activity
GO:0005251 IMP delayed rectifier potassium channel activity
GO:0005515 IPI:IEA protein binding
GO:0005783 IEA endoplasmic reticulum
GO:0005794 IDA Golgi apparatus
GO:0005886 IDA plasma membrane
GO:0005901 TAS caveola
GO:0006811 IEA ion transport
GO:0006813 IDA potassium ion transport
GO:0007268 TAS synaptic transmission
GO:0008076 IDA voltage-gated potassium channel complex
GO:0014704 IDA intercalated disc
GO:0015271 IDA outward rectifier potassium channel activity
GO:0016020 IEA membrane
GO:0019229 IEA regulation of vasoconstriction
GO:0019870 IEA potassium channel inhibitor activity
GO:0019901 IPI protein kinase binding
GO:0030018 IEA Z disc
GO:0042391 IDA regulation of membrane potential
GO:0043266 IMP regulation of potassium ion transport
GO:0043267 IEA negative regulation of potassium ion transport
GO:0045121 IDA membrane raft
GO:0046691 IEA intracellular canaliculus
GO:0048471 IEA perinuclear region of cytoplasm
GO:0050796 TAS regulation of insulin secretion
GO:0051259 IEA protein oligomerization
GO:0051260 IEA protein homooligomerization
GO:0051393 IPI alpha-actinin binding
GO:0051481 IEA negative regulation of cytosolic calcium ion concentration
GO:0055075 IEA potassium ion homeostasis
GO:0055085 IEA transmembrane transport
GO:0060081 IMP membrane hyperpolarization
GO:0060372 IMP regulation of atrial cardiac muscle cell membrane repolarization
GO:0071435 IDA potassium ion export
GO:0086014 IMP atrial cardiac muscle cell action potential
GO:0086089 IMP voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization
GO:0086091 IMP regulation of heart rate by cardiac conduction
GO:0097110 IPI scaffold protein binding
GO:1900087 IEA positive regulation of G1/S transition of mitotic cell cycle
GO:2000288 IEA positive regulation of myoblast proliferation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000060972 Kcna5-201 protein_coding Mus_musculus 0 1938
ENSMUST00000185333 Kcna6-201 protein_coding Mus_musculus 0 575
ENSMUST00000112242 Kcna6-003 protein_coding Mus_musculus 0 575
ENSMUST00000040751 Kcna6-001 nonsense_mediated_decay Mus_musculus 0 575
ENSDART00000088477 CABZ01083827.1-201 protein_coding Danio_rerio 0 481
ENSMUST00000055064 Kcna10-001 protein_coding Mus_musculus 0 388
ENSMUST00000052718 Kcna3-201 protein_coding Mus_musculus 0 383

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