C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: synaptotagmin I
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000261205 SYT1-001 ENSG00000067715 9606 + 12:78864669-79452006 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainBreastColonOvaryPlacentaTestisENST00000261205
Transcript ID Adrenal Brain Breast Colon Ovary Placenta Testis
ENST00000261205 0.246±0.00 70.258±3.90 0.288±0.00 0.838±0.27 0.597±0.06 0.207±0.00 0.771±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002BE CIL_0002BE_0002 CGP 12:78863993-79691097

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000149 ISS SNARE binding
GO:0001786 IEA phosphatidylserine binding
GO:0005215 IEA transporter activity
GO:0005509 IEA calcium ion binding
GO:0005513 TAS detection of calcium ion
GO:0005515 IPI:IEA protein binding
GO:0005516 IEA calmodulin binding
GO:0005543 IEA phospholipid binding
GO:0005544 ISS calcium-dependent phospholipid binding
GO:0005545 TAS 1-phosphatidylinositol binding
GO:0005546 IEA phosphatidylinositol-4,5-bisphosphate binding
GO:0005737 IEA cytoplasm
GO:0005886 TAS plasma membrane
GO:0007268 TAS synaptic transmission
GO:0007269 TAS neurotransmitter secretion
GO:0008021 TAS synaptic vesicle
GO:0008022 IEA protein C-terminus binding
GO:0014047 TAS glutamate secretion
GO:0016021 IEA integral component of membrane
GO:0016079 IEA synaptic vesicle exocytosis
GO:0017075 ISS syntaxin-1 binding
GO:0017157 TAS regulation of exocytosis
GO:0017158 IEA regulation of calcium ion-dependent exocytosis
GO:0019905 IEA syntaxin binding
GO:0030054 IEA cell junction
GO:0030141 IEA secretory granule
GO:0030276 IEA clathrin binding
GO:0030666 TAS endocytic vesicle membrane
GO:0030672 IEA synaptic vesicle membrane
GO:0031045 IEA dense core granule
GO:0031201 IEA SNARE complex
GO:0031340 IEA positive regulation of vesicle fusion
GO:0042734 IEA presynaptic membrane
GO:0042802 IEA identical protein binding
GO:0043005 ISS neuron projection
GO:0043229 IEA intracellular organelle
GO:0045956 IEA positive regulation of calcium ion-dependent exocytosis
GO:0048278 IEA vesicle docking
GO:0048306 IEA calcium-dependent protein binding
GO:0048791 ISS calcium ion-dependent exocytosis of neurotransmitter
GO:0050750 IDA low-density lipoprotein particle receptor binding
GO:0050806 ISS positive regulation of synaptic transmission
GO:0051260 TAS protein homooligomerization
GO:0051592 IEA response to calcium ion
GO:0051966 ISS regulation of synaptic transmission, glutamatergic
GO:0060076 IEA excitatory synapse
GO:0060201 TAS clathrin-sculpted acetylcholine transport vesicle membrane
GO:0060203 TAS clathrin-sculpted glutamate transport vesicle membrane
GO:0061202 TAS clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane
GO:0070083 TAS clathrin-sculpted monoamine transport vesicle membrane
GO:1903305 ISS regulation of regulated secretory pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000064054 Syt1-006 protein_coding Mus_musculus 0 3596
ENSMUST00000105276 Syt1-001 protein_coding Mus_musculus 0 3596
ENSDART00000041861 syt1a-001 protein_coding Danio_rerio 0 665
ENSMUST00000146618 Syt1-003 retained_intron Mus_musculus 0 412
ENSDART00000023562 SYT2 (2 of 4)-201 protein_coding Danio_rerio 0 412

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