C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: sterol regulatory element binding transcription factor 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000261646 SREBF1-002 ENSG00000072310 9606 - 17:17812073-17837002 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000261646
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000261646 5.926±0.00 11.856±0.00 1.828±0.00 10.679±0.00 5.066±3.68 2.918±0.07 1.812±1.13 6.851±0.00 11.148±0.00 14.035±0.00 3.249±0.00 16.514±11.86 8.919±2.43 7.313±0.87

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0009A0 CIL_0009A0_0001 VISTA 17:17235872-17840873
CIL_0000NM CIL_0000NM_0001 CGP 17:17505563-17811453
CIL_00003U CIL_00003U_0002 CGP 17:17681473-17837002
CIL_00003N CIL_00003N_0002 CGP 17:17810399-17972422

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000139 TAS Golgi membrane
GO:0003677 ISS DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005635 TAS nuclear envelope
GO:0005654 TAS nucleoplasm
GO:0005737 ISS cytoplasm
GO:0005783 IDA endoplasmic reticulum
GO:0005789 TAS endoplasmic reticulum membrane
GO:0005829 TAS cytosol
GO:0006351 IEA transcription, DNA-templated
GO:0006357 TAS regulation of transcription from RNA polymerase II promoter
GO:0006629 TAS lipid metabolic process
GO:0008610 ISS lipid biosynthetic process
GO:0009267 ISS cellular response to starvation
GO:0010867 ISS positive regulation of triglyceride biosynthetic process
GO:0016021 IEA integral component of membrane
GO:0031410 IEA cytoplasmic vesicle
GO:0032810 IDA sterol response element binding
GO:0044255 TAS cellular lipid metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046983 IEA protein dimerization activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000020846 Srebf1-005 protein_coding Mus_musculus 0 2649
ENSMUST00000134660 Srebf1-006 protein_coding Mus_musculus 0 2449
ENSMUST00000144942 Srebf1-007 protein_coding Mus_musculus 0 2307
ENSMUST00000154620 Srebf1-010 processed_transcript Mus_musculus 0 577
ENSMUST00000149238 Srebf1-001 processed_transcript Mus_musculus 0 534
ENSMUST00000156304 Srebf1-004 processed_transcript Mus_musculus 0 409
ENSMUST00000154925 Srebf1-002 processed_transcript Mus_musculus 0 309
ENSMUST00000136426 Srebf1-003 processed_transcript Mus_musculus 0 224

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