C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info

Description: potassium voltage-gated channel, subfamily H (eag-related), member 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000262186 KCNH2-001 ENSG00000055118 9606 - 7:150944961-150978315 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainColonHeartKidneyLungOvaryTestisENST00000262186
Transcript ID Adrenal Brain Colon Heart Kidney Lung Ovary Testis
ENST00000262186 0.546±0.00 1.672±0.98 1.168±1.07 7.506±5.88 0.320±0.00 0.698±0.00 3.549±0.00 5.928±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008T1 CIL_0008T1_0001 VISTA 7:150668461-151272977
CIL_0004OG CIL_0004OG_0001 CGP 7:150944961-151014588

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000155 IEA phosphorelay sensor kinase activity
GO:0000160 IEA phosphorelay signal transduction system
GO:0003064 TAS regulation of heart rate by hormone
GO:0004871 IEA signal transducer activity
GO:0005216 IEA ion channel activity
GO:0005242 IDA inward rectifier potassium channel activity
GO:0005249 IDA voltage-gated potassium channel activity
GO:0005251 IDA delayed rectifier potassium channel activity
GO:0005515 IPI:IEA protein binding
GO:0005635 IEA nuclear envelope
GO:0005737 IEA cytoplasm
GO:0005886 IDA plasma membrane
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006811 IEA ion transport
GO:0007165 IEA signal transduction
GO:0007268 TAS synaptic transmission
GO:0008076 IDA voltage-gated potassium channel complex
GO:0009986 IDA cell surface
GO:0016020 IEA membrane
GO:0023014 IEA signal transduction by phosphorylation
GO:0031625 IPI ubiquitin protein ligase binding
GO:0035690 IDA cellular response to drug
GO:0042391 IDA regulation of membrane potential
GO:0042802 IPI identical protein binding
GO:0042803 IPI protein homodimerization activity
GO:0055075 IDA potassium ion homeostasis
GO:0055085 IEA transmembrane transport
GO:0060048 IMP cardiac muscle contraction
GO:0060306 IDA regulation of membrane repolarization
GO:0060307 IMP regulation of ventricular cardiac muscle cell membrane repolarization
GO:0071435 IDA potassium ion export
GO:0071805 IDA potassium ion transmembrane transport
GO:0086005 IMP ventricular cardiac muscle cell action potential
GO:0086010 IDA membrane depolarization during action potential
GO:0086011 IDA membrane repolarization during action potential
GO:0086013 IMP membrane repolarization during cardiac muscle cell action potential
GO:0086091 IMP regulation of heart rate by cardiac conduction
GO:1901379 IDA regulation of potassium ion transmembrane transport
GO:1901380 IDA negative regulation of potassium ion transmembrane transport
GO:1901381 IDA positive regulation of potassium ion transmembrane transport
GO:1902282 IMP voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization
GO:1902303 IDA negative regulation of potassium ion export

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000036092 Kcnh2-001 protein_coding Mus_musculus 0 4865
ENSMUST00000115098 Kcnh2-002 protein_coding Mus_musculus 0 3319
ENSMUST00000145539 Kcnh6-004 nonsense_mediated_decay Mus_musculus 0 1365
ENSMUST00000001965 Kcnh6-001 protein_coding Mus_musculus 0 1365
ENSDART00000090809 kcnh6-201 protein_coding Danio_rerio 0 1027
ENSDART00000134201 kcnh6-001 protein_coding Danio_rerio 0 1027
ENSMUST00000142197 Kcnh2-004 processed_transcript Mus_musculus 0 784
ENSMUST00000129246 Kcnh2-005 processed_transcript Mus_musculus 0 774
ENSMUST00000106903 Kcnh6-002 protein_coding Mus_musculus 0 756
ENSDART00000084238 KCNH7 (4 of 6)-201 protein_coding Danio_rerio 0 568
ENSMUST00000126791 Kcnh2-003 processed_transcript Mus_musculus 0 435
ENSMUST00000140695 Kcnh6-003 processed_transcript Mus_musculus 1e-23 117
ENSMUST00000041415 Kcnh3-201 protein_coding Mus_musculus 0.00002 57

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