C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000262407 ITGA2B-001 ENSG00000005961 9606 - 17:44372183-44389505 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000262407
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000262407 1.052±0.00 0.256±0.00 0.041±0.00 0.199±0.16 0.234±0.00 0.231±0.12 0.088±0.00 0.073±0.00 0.021±0.00 2.701±2.49 0.157±0.09 0.580±0.06 0.810±0.08

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0009B6 CIL_0009B6_0001 VISTA 17:43966083-44567774
CIL_0007ST CIL_0007ST_0001 VISTA 17:44247434-44848646
CIL_0004D6 CIL_0004D6_0002 CGP 17:44353215-44389505
CIL_0005IZ CIL_0005IZ_0001 CGP 17:44372180-44503430

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002576 TAS platelet degranulation
GO:0002687 IEA positive regulation of leukocyte migration
GO:0005515 IPI protein binding
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0005925 IEA focal adhesion
GO:0007155 TAS cell adhesion
GO:0007160 IEA cell-matrix adhesion
GO:0007229 IDA integrin-mediated signaling pathway
GO:0007411 TAS axon guidance
GO:0007596 TAS blood coagulation
GO:0008305 IEA integrin complex
GO:0009897 IEA external side of plasma membrane
GO:0009986 IDA cell surface
GO:0030168 TAS platelet activation
GO:0030198 TAS extracellular matrix organization
GO:0031092 TAS platelet alpha granule membrane
GO:0042802 IPI identical protein binding
GO:0046872 IEA metal ion binding
GO:0050840 IEA extracellular matrix binding
GO:0070051 IEA fibrinogen binding
GO:0070062 IDA extracellular vesicular exosome
GO:0070527 IEA platelet aggregation
GO:0072562 IDA blood microparticle

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000103086 Itga2b-001 protein_coding Mus_musculus 0 2691
ENSMUST00000149519 Itga2b-002 processed_transcript Mus_musculus 0 1531
ENSMUST00000151625 Itga2b-007 processed_transcript Mus_musculus 0 643
ENSMUST00000130433 Itga2b-006 processed_transcript Mus_musculus 0 414
ENSMUST00000124767 Itga2b-005 processed_transcript Mus_musculus 0 327
ENSMUST00000131247 Itga2b-008 processed_transcript Mus_musculus 0 219

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