C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: aldo-keto reductase family 1, member B1 (aldose reductase)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000285930 AKR1B1-001 ENSG00000085662 9606 - 7:134442350-134459142 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000285930
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000285930 37.712±0.00 42.435±0.00 4.560±0.00 24.819±21.61 14.040±11.80 11.606±10.47 33.149±27.34 54.082±53.29 4.821±3.52 25.640±0.00 31.774±21.66 29.662±20.30 133.418±65.13 43.922±10.60

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002GW CIL_0002GW_0001 CGP 7:134289332-134459284
CIL_0002GX CIL_0002GX_0001 CGP 7:134442350-134541408

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004032 IEA alditol:NADP+ 1-oxidoreductase activity
GO:0004033 TAS aldo-keto reductase (NADP) activity
GO:0005615 TAS extracellular space
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0005975 TAS carbohydrate metabolic process
GO:0006700 TAS C21-steroid hormone biosynthetic process
GO:0006950 TAS response to stress
GO:0008202 TAS steroid metabolic process
GO:0009055 TAS electron carrier activity
GO:0043795 IDA glyceraldehyde oxidoreductase activity
GO:0044281 TAS small molecule metabolic process
GO:0044597 IMP daunorubicin metabolic process
GO:0044598 IMP doxorubicin metabolic process
GO:0055114 IEA oxidation-reduction process
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000166583 Gm6736-201 processed_pseudogene Mus_musculus 0 1035
ENSMUST00000122180 Gm12138-001 processed_pseudogene Mus_musculus 0 1029
ENSMUST00000102980 Akr1b3-001 protein_coding Mus_musculus 0 1029
ENSMUST00000186507 RP23-453N3.5-001 processed_pseudogene Mus_musculus 0 1024
ENSMUST00000118494 Gm5400-001 processed_pseudogene Mus_musculus 0 898
ENSMUST00000181879 Gm7678-001 processed_pseudogene Mus_musculus 0 763
ENSMUST00000121650 Gm5395-001 processed_pseudogene Mus_musculus 0 691
ENSMUST00000117065 Gm12015-001 processed_pseudogene Mus_musculus 0 680
ENSMUST00000007449 Akr1b7-001 protein_coding Mus_musculus 0 460
ENSMUST00000038383 Akr1b10-001 protein_coding Mus_musculus 0 455
ENSMUST00000118018 Gm13983-001 processed_pseudogene Mus_musculus 0 438
ENSMUST00000115051 Akr1b10-004 protein_coding Mus_musculus 0 374
ENSMUST00000139156 Akr1b10-002 nonsense_mediated_decay Mus_musculus 0 265
ENSMUST00000142761 Akr1b3-005 retained_intron Mus_musculus 1e-32 145
ENSMUST00000150561 Gm13857-002 processed_transcript Mus_musculus 0.00000001 66

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