C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: NEDD8 activating enzyme E1 subunit 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000290810 NAE1-001 ENSG00000159593 9606 - 16:66802875-66830997 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainColonHeartLiverMuscleOvaryPlacentaTestisENST00000290810
Transcript ID Adipose Bladder Brain Colon Heart Liver Muscle Ovary Placenta Testis
ENST00000290810 3.634±0.00 0.864±0.00 5.639±0.00 2.181±0.76 2.098±0.00 2.485±1.44 2.924±0.00 8.657±4.72 4.365±0.62 11.475±3.32

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007WN CIL_0007WN_0001 VISTA 16:66603173-67205657
CIL_0004IV CIL_0004IV_0001 CGP 16:66754976-66873256
CIL_0003LY CIL_0003LY_0002 CGP 16:66802875-66873256

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003824 IEA catalytic activity
GO:0005515 IPI protein binding
GO:0005634 IBA nucleus
GO:0005737 TAS cytoplasm
GO:0005829 IBA cytosol
GO:0005886 IEA plasma membrane
GO:0007165 TAS signal transduction
GO:0019781 IDA NEDD8 activating enzyme activity
GO:0031625 IPI ubiquitin protein ligase binding
GO:0033314 IDA mitotic DNA replication checkpoint
GO:0042981 IDA regulation of apoptotic process
GO:0043523 IDA regulation of neuron apoptotic process
GO:0045116 IEA protein neddylation
GO:0046982 IPI protein heterodimerization activity
GO:0051402 IDA neuron apoptotic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000034349 Nae1-001 protein_coding Mus_musculus 0 2407
ENSMUST00000162466 Nae1-004 protein_coding Mus_musculus 0 1917
ENSMUST00000160913 Nae1-003 retained_intron Mus_musculus 0 880
ENSMUST00000161462 Nae1-008 processed_transcript Mus_musculus 0 854
ENSMUST00000159330 Nae1-009 retained_intron Mus_musculus 0 749
ENSMUST00000159393 Nae1-002 retained_intron Mus_musculus 0 676
ENSMUST00000161474 Nae1-006 retained_intron Mus_musculus 0 553
ENSMUST00000160148 Nae1-010 retained_intron Mus_musculus 0 462
ENSMUST00000159702 Nae1-005 retained_intron Mus_musculus 0 370
ENSMUST00000161411 Nae1-011 retained_intron Mus_musculus 0 239
ENSMUST00000159696 Nae1-007 retained_intron Mus_musculus 0 206

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