C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: glutamate receptor, ionotropic, N-methyl D-aspartate 2C
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000293190 GRIN2C-001 ENSG00000161509 9606 - 17:74842023-74859875 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainBreastLiverOvaryPlacentaTestisENST00000293190
Transcript ID Brain Breast Liver Ovary Placenta Testis
ENST00000293190 3.320±0.00 0.036±0.00 0.021±0.00 0.192±0.11 1.458±0.00 1.340±0.63

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000286 CIL_000286_0001 CGP 17:74776483-74861504
CIL_0001FN CIL_0001FN_0001 CGP 17:74842023-74873031

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004970 IEA ionotropic glutamate receptor activity
GO:0004972 IBA N-methyl-D-aspartate selective glutamate receptor activity
GO:0005234 IBA:IEA extracellular-glutamate-gated ion channel activity
GO:0005261 IEA cation channel activity
GO:0005515 IPI protein binding
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006810 TAS transport
GO:0006812 IEA cation transport
GO:0007215 TAS glutamate receptor signaling pathway
GO:0007268 TAS synaptic transmission
GO:0008104 IEA protein localization
GO:0009611 IEA response to wounding
GO:0014069 IEA postsynaptic density
GO:0016020 IEA membrane
GO:0017146 IBA N-methyl-D-aspartate selective glutamate receptor complex
GO:0030054 IEA cell junction
GO:0030165 IEA PDZ domain binding
GO:0030425 IBA dendrite
GO:0033058 IEA directional locomotion
GO:0034220 IBA ion transmembrane transport
GO:0035235 IBA ionotropic glutamate receptor signaling pathway
GO:0035249 IBA synaptic transmission, glutamatergic
GO:0042177 IEA negative regulation of protein catabolic process
GO:0042391 IEA regulation of membrane potential
GO:0045211 IBA postsynaptic membrane
GO:0047485 IEA protein N-terminus binding
GO:0050885 IEA neuromuscular process controlling balance
GO:0060079 IEA regulation of excitatory postsynaptic membrane potential
GO:0098655 IEA cation transmembrane transport

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000003351 Grin2c-001 protein_coding Mus_musculus 0 4026
ENSMUST00000106554 Grin2c-201 protein_coding Mus_musculus 0 3838
ENSMUST00000002848 Grin2d-001 protein_coding Mus_musculus 0 1011
ENSDART00000110554 grin2ca-201 protein_coding Danio_rerio 0 850
ENSDART00000145215 grin2ca-001 protein_coding Danio_rerio 0 850

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