C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: runt related transcription factor 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000023673 Runx1-001 ENSMUSG00000022952 10090 - 16:92601466-92826149 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000023673
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000023673 0.693±0.13 0.200±0.05 0.033±0.00 2.238±0.91 0.795±0.20 0.112±0.06 0.104±0.02 0.479±0.48 2.806±0.42 0.118±0.04 1.130±0.28 0.143±0.05 0.035±0.02

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008ON CIL_0008ON_0002 VISTA 16:92040534-92642015
CIL_0007SX CIL_0007SX_0002 VISTA 16:92042784-92648394
CIL_0008OM CIL_0008OM_0002 VISTA 16:92044467-92645647
CIL_0008ZS CIL_0008ZS_0002 VISTA 16:92110151-92716672
CIL_00094R CIL_00094R_0002 VISTA 16:92127453-92730131
CIL_00078F CIL_00078F_0002 CGP 16:92485736-92826149

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000975 IEA regulatory region DNA binding
GO:0001501 IMP skeletal system development
GO:0001701 IMP in utero embryonic development
GO:0001889 IMP liver development
GO:0002318 IMP myeloid progenitor cell differentiation
GO:0003677 IDA DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0005509 IEA calcium ion binding
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005604 IDA basement membrane
GO:0005634 IDA nucleus
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0007417 IMP central nervous system development
GO:0008134 IEA transcription factor binding
GO:0009966 IMP regulation of signal transduction
GO:0030099 IEA myeloid cell differentiation
GO:0030182 IMP neuron differentiation
GO:0030853 IEA negative regulation of granulocyte differentiation
GO:0030854 IEA positive regulation of granulocyte differentiation
GO:0031069 IMP hair follicle morphogenesis
GO:0035162 IMP embryonic hemopoiesis
GO:0042803 IEA protein homodimerization activity
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046982 IEA protein heterodimerization activity
GO:0048266 IMP behavioral response to pain
GO:0048666 IMP neuron development
GO:0060216 IMP definitive hemopoiesis
GO:0070491 IPI repressing transcription factor binding
GO:0071336 IMP regulation of hair follicle cell proliferation
GO:0071560 IDA cellular response to transforming growth factor beta stimulus
GO:2000872 IEA positive regulation of progesterone secretion

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000130697 RUNX1 (2 of 2)-201 protein_coding Danio_rerio 0 267
ENST00000300305 RUNX1-002 protein_coding Homo_sapiens 0 1825
ENST00000308873 RUNX3-001 protein_coding Homo_sapiens 0 342
ENST00000338888 RUNX3-002 protein_coding Homo_sapiens 0 342
ENST00000344691 RUNX1-001 protein_coding Homo_sapiens 0 1827
ENST00000358356 RUNX1-005 protein_coding Homo_sapiens 0 1020
ENST00000399237 RUNX1-012 protein_coding Homo_sapiens 0 1016
ENST00000399240 RUNX1-009 protein_coding Homo_sapiens 0 811
ENST00000399916 RUNX3-201 protein_coding Homo_sapiens 0 342
ENST00000416754 RUNX1-004 protein_coding Homo_sapiens 1e-37 159
ENST00000437180 RUNX1-201 protein_coding Homo_sapiens 0 1825
ENST00000455571 RUNX1-010 protein_coding Homo_sapiens 0 859
ENST00000469087 RUNX1-007 retained_intron Homo_sapiens 0 316
ENST00000475045 RUNX1-013 protein_coding Homo_sapiens 6e-17 94
ENST00000482318 RUNX1-003 nonsense_mediated_decay Homo_sapiens 0 1435

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