C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: presenilin associated, rhomboid-like
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000317096 PARL-001 ENSG00000175193 9606 - 3:183829385-183884907 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000317096
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000317096 15.492±0.00 14.896±0.00 8.240±3.94 16.495±0.00 4.886±0.55 6.212±4.80 6.816±0.00 3.809±1.12 6.084±0.00 8.382±0.00 16.028±3.47 15.070±5.91 8.095±0.48

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005G0 CIL_0005G0_0001 CGP 3:183815876-183884933

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004175 IGI endopeptidase activity
GO:0004252 IEA serine-type endopeptidase activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005739 IDA mitochondrion
GO:0005743 TAS mitochondrial inner membrane
GO:0006508 IGI proteolysis
GO:0016021 IEA integral component of membrane
GO:0033619 NAS membrane protein proteolysis
GO:0090201 IEA negative regulation of release of cytochrome c from mitochondria
GO:1903214 NAS regulation of protein targeting to mitochondrion
GO:2000377 IMP regulation of reactive oxygen species metabolic process
GO:2001243 IEA negative regulation of intrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000048642 Parl-001 protein_coding Mus_musculus 0 1358
ENSMUST00000136252 Parl-002 nonsense_mediated_decay Mus_musculus 0 776
ENSMUST00000136700 Parl-005 processed_transcript Mus_musculus 0 758
ENSMUST00000117482 Gm14994-001 processed_pseudogene Mus_musculus 0 562
ENSMUST00000120117 Gm13181-001 processed_pseudogene Mus_musculus 0 560
ENSMUST00000133153 Parl-009 nonsense_mediated_decay Mus_musculus 0 536
ENSMUST00000123070 Parl-003 retained_intron Mus_musculus 0 462
ENSMUST00000126001 Parl-008 retained_intron Mus_musculus 0 396
ENSMUST00000152887 Parl-004 processed_transcript Mus_musculus 0 394
ENSMUST00000155832 Parl-007 retained_intron Mus_musculus 0 326
ENSMUST00000153275 Parl-010 retained_intron Mus_musculus 0 315
ENSMUST00000143648 Parl-006 retained_intron Mus_musculus 0 287

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