C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: protein kinase, interferon-inducible double stranded RNA dependent activator
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000325748 PRKRA-001 ENSG00000180228 9606 - 2:178431414-178451231 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000325748
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000325748 13.807±0.00 13.018±0.00 1.782±0.00 13.384±7.53 5.447±3.46 11.133±7.85 7.915±6.54 20.987±0.00 2.407±0.11 10.309±0.00 13.010±8.68 10.624±7.42 5.977±3.66 20.529±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000Z1 CIL_0000Z1_0001 CGP 2:178194481-178451512
CIL_0000Z0 CIL_0000Z0_0001 CGP 2:178431414-178461390

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005622 IEA intracellular
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0006468 IEA protein phosphorylation
GO:0006955 TAS immune response
GO:0008047 TAS enzyme activator activity
GO:0008285 TAS negative regulation of cell proliferation
GO:0009615 TAS response to virus
GO:0010467 TAS gene expression
GO:0016020 IDA membrane
GO:0016301 IEA kinase activity
GO:0030422 IDA production of siRNA involved in RNA interference
GO:0034599 IEA cellular response to oxidative stress
GO:0042473 IEA outer ear morphogenesis
GO:0042474 IEA middle ear morphogenesis
GO:0042803 IPI protein homodimerization activity
GO:0043085 TAS positive regulation of catalytic activity
GO:0044822 IDA poly(A) RNA binding
GO:0048705 IEA skeletal system morphogenesis
GO:2001244 IEA positive regulation of intrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000002808 Prkra-001 protein_coding Mus_musculus 0 1415
ENSMUST00000140493 Prkra-002 processed_transcript Mus_musculus 0 387

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