C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: hepatocyte growth factor-regulated tyrosine kinase substrate
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000329138 HGS-001 ENSG00000185359 9606 + 17:81683932-81702119 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000329138
Transcript ID Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000329138 8.655±0.00 2.611±0.00 5.751±0.00 1.490±0.00 4.979±0.00 0.565±0.00 0.859±0.00 3.496±0.21 4.439±0.00 10.551±9.31 2.989±0.00 16.341±5.08 14.595±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002FQ CIL_0002FQ_0001 CGP 17:81666364-81683924
CIL_0003BA CIL_0003BA_0001 CGP 17:81681174-81703138
CIL_0004BU CIL_0004BU_0001 CGP 17:81683326-81707526

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005737 IDA cytoplasm
GO:0005768 IDA endosome
GO:0005769 IDA early endosome
GO:0005829 TAS cytosol
GO:0006622 IMP protein targeting to lysosome
GO:0006886 IEA intracellular protein transport
GO:0007165 TAS signal transduction
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0008285 TAS negative regulation of cell proliferation
GO:0008333 IEA endosome to lysosome transport
GO:0010324 IMP membrane invagination
GO:0010628 IMP positive regulation of gene expression
GO:0016020 IEA membrane
GO:0016197 NAS endosomal transport
GO:0019904 IPI protein domain specific binding
GO:0030141 IEA secretory granule
GO:0042059 TAS negative regulation of epidermal growth factor receptor signaling pathway
GO:0042176 TAS regulation of protein catabolic process
GO:0043231 IDA intracellular membrane-bounded organelle
GO:0046426 IDA negative regulation of JAK-STAT cascade
GO:0046872 IEA metal ion binding
GO:0061024 TAS membrane organization
GO:0070062 IDA extracellular vesicular exosome
GO:0072657 IMP protein localization to membrane

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000026900 Hgs-201 protein_coding Mus_musculus 0 2682
ENSMUST00000106203 Hgs-002 protein_coding Mus_musculus 0 2663
ENSMUST00000106205 Hgs-001 protein_coding Mus_musculus 0 2643
ENSMUST00000141826 Hgs-003 processed_transcript Mus_musculus 0 911
ENSMUST00000135231 Hgs-005 protein_coding Mus_musculus 0 621
ENSMUST00000140862 Hgs-004 protein_coding Mus_musculus 0 540
ENSDART00000056622 hgs-202 protein_coding Danio_rerio 0 468
ENSDART00000131913 hgs-001 protein_coding Danio_rerio 0 466
ENSDART00000019661 hgs-201 protein_coding Danio_rerio 0 459

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