C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: sterol regulatory element binding transcription factor 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000355815 SREBF1-003 ENSG00000072310 9606 - 17:17812073-17836987 protein_coding

Homo sapiens EnsemblGRCh38

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Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainBreastKidneyLiverMuscleOvaryPlacentaTestisENST00000355815
Transcript ID Brain Breast Kidney Liver Muscle Ovary Placenta Testis
ENST00000355815 11.175±7.67 30.994±0.00 17.261±0.00 13.434±11.05 4.899±2.50 22.628±16.84 3.779±0.24 12.074±2.06

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0009A0 CIL_0009A0_0001 VISTA 17:17235872-17840873
CIL_0000NM CIL_0000NM_0001 CGP 17:17505563-17811453
CIL_00003U CIL_00003U_0002 CGP 17:17681473-17837002
CIL_00003N CIL_00003N_0002 CGP 17:17810399-17972422

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0000139 TAS Golgi membrane
GO:0003062 IEA regulation of heart rate by chemical signal
GO:0003677 ISS DNA binding
GO:0003682 IEA chromatin binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005635 TAS nuclear envelope
GO:0005654 TAS nucleoplasm
GO:0005737 ISS cytoplasm
GO:0005783 IDA endoplasmic reticulum
GO:0005789 TAS endoplasmic reticulum membrane
GO:0005829 TAS cytosol
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006357 TAS regulation of transcription from RNA polymerase II promoter
GO:0006629 TAS lipid metabolic process
GO:0007568 IEA aging
GO:0007623 IEA circadian rhythm
GO:0008203 IEA cholesterol metabolic process
GO:0008286 IEA insulin receptor signaling pathway
GO:0008610 ISS lipid biosynthetic process
GO:0009267 ISS cellular response to starvation
GO:0009749 IEA response to glucose
GO:0010867 ISS positive regulation of triglyceride biosynthetic process
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0019217 IEA regulation of fatty acid metabolic process
GO:0019901 IEA protein kinase binding
GO:0030324 IEA lung development
GO:0031065 IEA positive regulation of histone deacetylation
GO:0031410 IEA cytoplasmic vesicle
GO:0032094 IEA response to food
GO:0032403 IEA protein complex binding
GO:0032526 IEA response to retinoic acid
GO:0032570 IEA response to progesterone
GO:0032810 IDA sterol response element binding
GO:0032869 IEA cellular response to insulin stimulus
GO:0033762 IEA response to glucagon
GO:0033993 IEA response to lipid
GO:0042493 IEA response to drug
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0043234 IEA protein complex
GO:0043434 IEA response to peptide hormone
GO:0043565 IEA sequence-specific DNA binding
GO:0044212 IEA transcription regulatory region DNA binding
GO:0044255 TAS cellular lipid metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0045542 IEA positive regulation of cholesterol biosynthetic process
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046676 IEA negative regulation of insulin secretion
GO:0046983 IEA protein dimerization activity
GO:0050796 IEA regulation of insulin secretion
GO:0051591 IEA response to cAMP
GO:0070542 IEA response to fatty acid
GO:0071398 IEA cellular response to fatty acid

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000020846 Srebf1-005 protein_coding Mus_musculus 0 2586
ENSMUST00000134660 Srebf1-006 protein_coding Mus_musculus 0 2449
ENSMUST00000144942 Srebf1-007 protein_coding Mus_musculus 0 2359
ENSMUST00000154620 Srebf1-010 processed_transcript Mus_musculus 0 577
ENSMUST00000149238 Srebf1-001 processed_transcript Mus_musculus 0 534
ENSMUST00000156304 Srebf1-004 processed_transcript Mus_musculus 0 409
ENSMUST00000154925 Srebf1-002 processed_transcript Mus_musculus 0 309
ENSMUST00000136426 Srebf1-003 processed_transcript Mus_musculus 0 224

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