C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: regulatory factor X, 3 (influences HLA class II expression)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000358730 RFX3-005 ENSG00000080298 9606 - 9:3247037-3395596 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; ColonLungOvaryPlacentaENST00000358730
Transcript ID Colon Lung Ovary Placenta
ENST00000358730 0.483±0.00 1.698±0.00 0.827±0.28 0.166±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000NH CIL_0000NH_0001 CGP 9:2720469-3526004
CIL_0009AI CIL_0009AI_0001 VISTA 9:3101031-3702562

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000790 IDA nuclear chromatin
GO:0003677 IEA:TAS DNA binding
GO:0003700 NAS sequence-specific DNA binding transcription factor activity
GO:0003705 TAS RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IEA:IC nucleus
GO:0005667 IC transcription factor complex
GO:0006355 ISS:IEA regulation of transcription, DNA-templated
GO:0006366 TAS transcription from RNA polymerase II promoter
GO:0031018 ISS endocrine pancreas development
GO:0042384 ISS cilium assembly
GO:0044212 IDA transcription regulatory region DNA binding
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 ISS positive regulation of transcription from RNA polymerase II promoter
GO:0048469 ISS cell maturation
GO:0050796 ISS regulation of insulin secretion
GO:0060285 ISS cilium-dependent cell motility
GO:0060287 ISS epithelial cilium movement involved in determination of left/right asymmetry
GO:2000078 ISS positive regulation of type B pancreatic cell development

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000165566 Rfx3-201 protein_coding Mus_musculus 0 2902
ENSMUST00000172907 Rfx3-004 protein_coding Mus_musculus 0 2902
ENSMUST00000174850 Rfx3-001 protein_coding Mus_musculus 0 2902
ENSMUST00000172498 Rfx3-006 processed_transcript Mus_musculus 0 2095
ENSMUST00000046898 Rfx3-003 protein_coding Mus_musculus 0 2095
ENSMUST00000173863 Rfx3-005 nonsense_mediated_decay Mus_musculus 0 965
ENSMUST00000173161 Rfx3-002 retained_intron Mus_musculus 0 957

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