C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: regulatory factor X, 3 (influences HLA class II expression)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000174850 Rfx3-001 ENSMUSG00000040929 10090 - 19:27768139-28011140 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainColonHeartOvaryTestisENSMUST00000174850
Transcript ID Adipose Adrenal Brain Colon Heart Ovary Testis
ENSMUST00000174850 0.504±0.00 0.304±0.00 4.696±0.00 0.154±0.00 0.152±0.00 1.175±0.19 5.909±0.45

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000NH CIL_0000NH_0002 CGP 19:27388702-28011166
CIL_0009AI CIL_0009AI_0002 VISTA 19:27604248-28205597
CIL_0000F0 CIL_0000F0_0002 CGP 19:27761721-28680077

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000790 IDA nuclear chromatin
GO:0003677 IEA DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005667 IC transcription factor complex
GO:0006351 IMP transcription, DNA-templated
GO:0006355 IMP regulation of transcription, DNA-templated
GO:0007368 IMP determination of left/right symmetry
GO:0031018 IMP endocrine pancreas development
GO:0042384 IMP cilium assembly
GO:0044212 IDA transcription regulatory region DNA binding
GO:0045892 ISS negative regulation of transcription, DNA-templated
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0048469 IMP cell maturation
GO:0050796 IMP regulation of insulin secretion
GO:0060285 IMP cilium-dependent cell motility
GO:0060287 IMP epithelial cilium movement involved in determination of left/right asymmetry
GO:0072560 IMP type B pancreatic cell maturation
GO:2000078 IMP positive regulation of type B pancreatic cell development

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000041236 rfx3-201 protein_coding Danio_rerio 0.000000000003 79
ENSDART00000144882 rfx3-001 protein_coding Danio_rerio 0.000000000003 79
ENST00000302303 RFX3-201 protein_coding Homo_sapiens 0 1764
ENST00000358730 RFX3-005 protein_coding Homo_sapiens 0 2902
ENST00000382004 RFX3-006 protein_coding Homo_sapiens 0 3572
ENST00000420720 RFX3-010 protein_coding Homo_sapiens 0 527
ENST00000442560 RFX3-009 protein_coding Homo_sapiens 0 527
ENST00000449190 RFX3-004 protein_coding Homo_sapiens 0 579
ENST00000449234 RFX3-007 protein_coding Homo_sapiens 0 472
ENST00000451859 RFX3-002 protein_coding Homo_sapiens 0 808
ENST00000457373 RFX3-003 protein_coding Homo_sapiens 0 669
ENST00000458034 RFX3-008 protein_coding Homo_sapiens 0 942
ENST00000617270 RFX3-202 protein_coding Homo_sapiens 0 3860

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