C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: low density lipoprotein receptor class A domain containing 4
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000359446 LDLRAD4-002 ENSG00000168675 9606 + 18:13278103-13652754 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverMuscleOvaryPlacentaTestisENST00000359446
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Muscle Ovary Placenta Testis
ENST00000359446 0.917±0.00 1.282±0.00 0.878±0.00 3.524±0.00 2.006±0.43 0.913±0.00 2.243±0.00 0.687±0.00 0.783±0.00 0.955±0.63 0.979±0.00 0.904±0.37 2.753±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000LB CIL_0000LB_0001 CGP 18:12991362-13652755
CIL_0007Z8 CIL_0007Z8_0001 VISTA 18:13081739-13682600
CIL_0005Q2 CIL_0005Q2_0002 CGP 18:13217498-13726663

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005515 IPI:IEA protein binding
GO:0005768 IEA endosome
GO:0010719 IMP negative regulation of epithelial to mesenchymal transition
GO:0010991 IDA negative regulation of SMAD protein complex assembly
GO:0016021 NAS integral component of membrane
GO:0030336 IMP negative regulation of cell migration
GO:0030512 IDA negative regulation of transforming growth factor beta receptor signaling pathway
GO:0031901 IDA early endosome membrane
GO:0060394 IDA negative regulation of pathway-restricted SMAD protein phosphorylation
GO:0070412 IPI R-SMAD binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000063775 Ldlrad4-201 protein_coding Mus_musculus 0 1426
ENSMUST00000042852 Fam210a-001 protein_coding Mus_musculus 0 254
ENSDART00000103683 LDLRAD4 (2 of 2)-201 protein_coding Danio_rerio 9e-37 161

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