C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: ryanodine receptor 1 (skeletal)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000359596 RYR1-010 ENSG00000196218 9606 + 19:38433830-38587420 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainLiverMuscleOvaryTestisENST00000359596
Transcript ID Brain Liver Muscle Ovary Testis
ENST00000359596 0.061±0.00 0.002±0.00 93.459±0.00 0.068±0.00 0.565±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001666 IDA response to hypoxia
GO:0002020 IEA protease binding
GO:0003151 ISS outflow tract morphogenesis
GO:0005216 IEA ion channel activity
GO:0005219 ISS:IEA ryanodine-sensitive calcium-release channel activity
GO:0005245 ISS voltage-gated calcium channel activity
GO:0005262 ISS:IEA calcium channel activity
GO:0005509 IEA calcium ion binding
GO:0005515 IPI:IEA protein binding
GO:0005516 ISS calmodulin binding
GO:0005737 IDA cytoplasm
GO:0005790 IEA smooth endoplasmic reticulum
GO:0005886 IDA plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0005938 IDA cell cortex
GO:0006811 IEA ion transport
GO:0006816 ISS calcium ion transport
GO:0006874 IEA cellular calcium ion homeostasis
GO:0006936 ISS muscle contraction
GO:0014701 TAS junctional sarcoplasmic reticulum membrane
GO:0014802 ISS terminal cisterna
GO:0014808 ISS release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
GO:0015278 TAS calcium-release channel activity
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0016529 ISS sarcoplasmic reticulum
GO:0019899 IEA enzyme binding
GO:0030314 IEA junctional membrane complex
GO:0030315 IEA T-tubule
GO:0031000 ISS response to caffeine
GO:0031674 IDA I band
GO:0033017 ISS sarcoplasmic reticulum membrane
GO:0034220 TAS ion transmembrane transport
GO:0043234 IEA protein complex
GO:0043588 ISS skin development
GO:0043931 ISS ossification involved in bone maturation
GO:0048741 ISS skeletal muscle fiber development
GO:0051209 ISS release of sequestered calcium ion into cytosol
GO:0051480 ISS cytosolic calcium ion homeostasis
GO:0055085 TAS:IEA transmembrane transport
GO:0070062 IDA extracellular vesicular exosome
GO:0070588 IEA calcium ion transmembrane transport
GO:0071313 ISS cellular response to caffeine

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000179893 Ryr1-202 protein_coding Mus_musculus 0 18100
ENSMUST00000032813 Ryr1-201 protein_coding Mus_musculus 0 18070
ENSDART00000036015 ryr1b-201 protein_coding Danio_rerio 0 3415
ENSDART00000014749 ryr1a-201 protein_coding Danio_rerio 0 922
ENSDART00000137089 ryr1a-001 protein_coding Danio_rerio 0 922
ENSDART00000147464 ryr3-001 protein_coding Danio_rerio 0 708
ENSDART00000077838 ryr3-201 protein_coding Danio_rerio 0 433
ENSDART00000078464 CABZ01065506.1-201 protein_coding Danio_rerio 0 409
ENSDART00000149737 ryr2b-001 protein_coding Danio_rerio 0 405
ENSDART00000122570 protein_coding Danio_rerio 0 291

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