C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: sphingomyelin synthase 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000361781 SGMS1-003 ENSG00000198964 9606 - 10:50305600-50623983 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000361781
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000361781 3.908±0.00 1.622±0.00 1.316±0.00 3.595±1.12 3.882±1.35 4.875±0.00 3.271±2.45 13.048±0.00 1.648±0.04 9.532±0.00 1.675±0.00 3.058±1.55 3.726±0.53 5.252±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000IG CIL_0000IG_0001 CGP 10:50182778-50625163

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000138 IDA Golgi trans cisterna
GO:0000139 TAS Golgi membrane
GO:0003824 IEA catalytic activity
GO:0005515 IEA protein binding
GO:0005634 TAS nucleus
GO:0005783 TAS endoplasmic reticulum
GO:0005886 TAS plasma membrane
GO:0006665 TAS sphingolipid metabolic process
GO:0006686 IDA sphingomyelin biosynthetic process
GO:0006915 IEA apoptotic process
GO:0006954 IEA inflammatory response
GO:0010628 IEA positive regulation of gene expression
GO:0016020 IDA:IEA membrane
GO:0016021 IEA integral component of membrane
GO:0016049 IDA cell growth
GO:0016301 IEA kinase activity
GO:0016310 IEA phosphorylation
GO:0030148 TAS sphingolipid biosynthetic process
GO:0030173 IDA integral component of Golgi membrane
GO:0033188 IMP sphingomyelin synthase activity
GO:0044281 TAS small molecule metabolic process
GO:0047493 IDA ceramide cholinephosphotransferase activity
GO:0071222 IEA cellular response to lipopolysaccharide
GO:0071356 IEA cellular response to tumor necrosis factor
GO:2001237 IEA negative regulation of extrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000142618 Sgms1-002 protein_coding Mus_musculus 0 3406
ENSMUST00000099514 Sgms1-001 protein_coding Mus_musculus 0 3406
ENSMUST00000151289 Sgms1-004 protein_coding Mus_musculus 0 2900
ENSMUST00000134415 Sgms1-007 nonsense_mediated_decay Mus_musculus 0 1162
ENSMUST00000152340 Sgms1-003 nonsense_mediated_decay Mus_musculus 0 1162
ENSMUST00000124012 Sgms1-005 retained_intron Mus_musculus 0 1142
ENSMUST00000151822 Sgms1-014 protein_coding Mus_musculus 0 315

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