C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: APEX nuclease (apurinic/apyrimidinic endonuclease) 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000374987 APEX2-001 ENSG00000169188 9606 + X:55000357-55009057 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000374987
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000374987 4.800±0.00 4.801±0.00 0.261±0.00 1.271±0.75 3.907±0.00 2.571±0.00 2.521±0.00 4.949±0.00 2.116±1.35 2.117±1.61 1.524±1.22 4.821±3.04 5.654±1.67 2.156±1.11

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000YC CIL_0000YC_0001 CGP X:55000357-55031064

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000737 IEA DNA catabolic process, endonucleolytic
GO:0000738 IBA DNA catabolic process, exonucleolytic
GO:0003677 IEA DNA binding
GO:0003906 IBA DNA-(apurinic or apyrimidinic site) lyase activity
GO:0004518 IEA nuclease activity
GO:0005634 IBA nucleus
GO:0005739 IEA mitochondrion
GO:0005743 IEA mitochondrial inner membrane
GO:0006281 IEA DNA repair
GO:0006284 IBA base-excision repair
GO:0006310 IEA DNA recombination
GO:0007049 IEA cell cycle
GO:0008270 IEA zinc ion binding
GO:0008311 IBA double-stranded DNA 3'-5' exodeoxyribonuclease activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000026303 Apex2-201 protein_coding Mus_musculus 0 1469
ENSMUST00000112720 Apex2-001 protein_coding Mus_musculus 0 1469
ENSMUST00000112721 Apex2-004 protein_coding Mus_musculus 0 1376
ENSMUST00000152332 Apex2-006 retained_intron Mus_musculus 0 1312
ENSMUST00000112719 Apex2-005 protein_coding Mus_musculus 0 767
ENSMUST00000112727 Apex2-003 protein_coding Mus_musculus 0 767
ENSMUST00000112725 Apex2-002 protein_coding Mus_musculus 0 767
ENSMUST00000140207 Apex2-009 protein_coding Mus_musculus 0 713
ENSMUST00000138958 Apex2-008 processed_transcript Mus_musculus 0 680
ENSMUST00000057256 6030458C11Rik-201 protein_coding Mus_musculus 0.0000004 62

Loading