C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: patched 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000375274 PTCH1-007 ENSG00000185920 9606 - 9:95446159-95516965 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; HeartPlacentaTestisENST00000375274
Transcript ID Heart Placenta Testis
ENST00000375274 0.225±0.00 0.666±0.00 1.591±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002J8 CIL_0002J8_0001 CGP 9:95099054-95517057
CIL_00086R CIL_00086R_0001 VISTA 9:95195577-95797123
CIL_0008KR CIL_0008KR_0001 VISTA 9:95212060-95813032
CIL_0002J7 CIL_0002J7_0001 CGP 9:95442980-96014571

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IMP negative regulation of transcription from RNA polymerase II promoter
GO:0005119 IPI smoothened binding
GO:0005515 IPI protein binding
GO:0005794 IDA Golgi apparatus
GO:0005886 IDA plasma membrane
GO:0005901 IDA caveola
GO:0007224 ISS smoothened signaling pathway
GO:0007420 ISS brain development
GO:0008158 IEA hedgehog receptor activity
GO:0008589 ISS regulation of smoothened signaling pathway
GO:0009887 ISS organ morphogenesis
GO:0009953 ISS dorsal/ventral pattern formation
GO:0010875 IDA positive regulation of cholesterol efflux
GO:0015485 IDA cholesterol binding
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0016485 ISS protein processing
GO:0021532 IMP neural tube patterning
GO:0021997 ISS neural plate axis specification
GO:0030326 ISS embryonic limb morphogenesis
GO:0030332 IPI cyclin binding
GO:0035108 IMP limb morphogenesis
GO:0040015 ISS negative regulation of multicellular organism growth
GO:0043231 IDA intracellular membrane-bounded organelle
GO:0043433 IMP negative regulation of sequence-specific DNA binding transcription factor activity
GO:0045668 IMP negative regulation of osteoblast differentiation
GO:0045879 ISS negative regulation of smoothened signaling pathway
GO:0048471 IDA perinuclear region of cytoplasm
GO:0060037 IMP pharyngeal system development
GO:0061053 IMP somite development
GO:0071397 ISS cellular response to cholesterol
GO:0072001 IEP renal system development
GO:0072661 IDA protein targeting to plasma membrane
GO:0097108 IPI hedgehog family protein binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000021921 Ptch1-201 protein_coding Mus_musculus 0 5123
ENSDART00000121923 ptch1-202 protein_coding Danio_rerio 0 665
ENSDART00000007640 ptch1-201 protein_coding Danio_rerio 0 665
ENSDART00000148258 ptch1-001 protein_coding Danio_rerio 0 665

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