C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: TNF receptor-associated factor 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000392745 TRAF3-005 ENSG00000131323 9606 + 14:102777557-102906261 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BreastColonHeartKidneyLiverLungOvaryENST00000392745
Transcript ID Breast Colon Heart Kidney Liver Lung Ovary
ENST00000392745 1.911±0.00 2.738±0.00 0.227±0.00 1.287±0.00 1.453±0.00 1.152±0.00 1.171±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0009AG CIL_0009AG_0001 VISTA 14:102447254-103047442
CIL_00040T CIL_00040T_0001 CGP 14:102777476-102933596

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001817 ISS regulation of cytokine production
GO:0002224 ISS toll-like receptor signaling pathway
GO:0002756 TAS MyD88-independent toll-like receptor signaling pathway
GO:0004842 IEA ubiquitin-protein transferase activity
GO:0004871 TAS signal transducer activity
GO:0005164 IPI tumor necrosis factor receptor binding
GO:0005515 IPI:IEA protein binding
GO:0005739 IEA mitochondrion
GO:0005768 IEA endosome
GO:0005829 TAS cytosol
GO:0006915 IEA apoptotic process
GO:0007165 TAS:IEA signal transduction
GO:0008063 IEA Toll signaling pathway
GO:0008270 IEA zinc ion binding
GO:0009898 ISS cytoplasmic side of plasma membrane
GO:0016567 IEA protein ubiquitination
GO:0016874 IEA ligase activity
GO:0030162 IMP regulation of proteolysis
GO:0031625 IPI ubiquitin protein ligase binding
GO:0031996 IPI thioesterase binding
GO:0032088 IEA:IMP negative regulation of NF-kappaB transcription factor activity
GO:0032480 TAS negative regulation of type I interferon production
GO:0032648 ISS regulation of interferon-beta production
GO:0033209 IEA:IMP tumor necrosis factor-mediated signaling pathway
GO:0034138 TAS toll-like receptor 3 signaling pathway
GO:0034142 TAS toll-like receptor 4 signaling pathway
GO:0035631 ISS CD40 receptor complex
GO:0035666 TAS TRIF-dependent toll-like receptor signaling pathway
GO:0042981 IEA regulation of apoptotic process
GO:0045087 IEA:TAS innate immune response
GO:0050688 IEA:ISS regulation of defense response to virus

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000021706 Traf3-001 protein_coding Mus_musculus 0 2468
ENSMUST00000143395 Traf3-004 retained_intron Mus_musculus 0 1882
ENSMUST00000060274 Traf3-201 protein_coding Mus_musculus 0 1650
ENSMUST00000117269 Traf3-002 protein_coding Mus_musculus 0 1650

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