C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: NEDD8 activating enzyme E1 subunit 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000394074 NAE1-004 ENSG00000159593 9606 - 16:66802912-66830955 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000394074
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000394074 7.672±0.00 0.853±0.00 7.412±4.38 6.467±0.00 7.336±0.00 1.796±0.00 7.501±0.00 4.459±0.00 2.049±0.25 2.298±0.00 3.770±2.24 4.356±0.18 18.469±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007WN CIL_0007WN_0001 VISTA 16:66603173-67205657
CIL_0004IV CIL_0004IV_0001 CGP 16:66754976-66873256
CIL_0003LY CIL_0003LY_0002 CGP 16:66802875-66873256

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005634 IBA nucleus
GO:0005737 TAS cytoplasm
GO:0005829 IBA cytosol
GO:0005886 IEA plasma membrane
GO:0007165 TAS signal transduction
GO:0019781 IDA NEDD8 activating enzyme activity
GO:0031625 IPI ubiquitin protein ligase binding
GO:0033314 IDA mitotic DNA replication checkpoint
GO:0042981 IDA regulation of apoptotic process
GO:0043523 IDA regulation of neuron apoptotic process
GO:0045116 IEA protein neddylation
GO:0046982 IPI protein heterodimerization activity
GO:0051402 IDA neuron apoptotic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000034349 Nae1-001 protein_coding Mus_musculus 0 2135
ENSMUST00000162466 Nae1-004 protein_coding Mus_musculus 0 1882
ENSMUST00000160913 Nae1-003 retained_intron Mus_musculus 0 880
ENSMUST00000161462 Nae1-008 processed_transcript Mus_musculus 0 819
ENSMUST00000159330 Nae1-009 retained_intron Mus_musculus 0 730
ENSMUST00000159393 Nae1-002 retained_intron Mus_musculus 0 676
ENSMUST00000161474 Nae1-006 retained_intron Mus_musculus 0 553
ENSMUST00000160148 Nae1-010 retained_intron Mus_musculus 0 462
ENSMUST00000161411 Nae1-011 retained_intron Mus_musculus 0 239
ENSMUST00000159696 Nae1-007 retained_intron Mus_musculus 0 206

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