C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: retinoic acid receptor, alpha
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000394089 RARA-002 ENSG00000131759 9606 + 17:40318281-40356331 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000394089
Transcript ID Adipose Adrenal Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000394089 9.775±0.00 8.075±0.00 5.703±4.42 7.884±0.00 2.165±0.00 0.436±0.00 0.449±0.00 1.069±0.00 7.934±0.00 15.667±5.70 6.503±1.55 7.772±0.82

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00098Y CIL_00098Y_0001 VISTA 17:39768583-40372873
CIL_0002GL CIL_0002GL_0001 CGP 17:40287633-40357643
CIL_00050G CIL_00050G_0001 CGP 17:40309192-40363815

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000790 IDA nuclear chromatin
GO:0001972 IDA retinoic acid binding
GO:0003700 IDA:IEA sequence-specific DNA binding transcription factor activity
GO:0003707 IEA steroid hormone receptor activity
GO:0003708 IDA retinoic acid receptor activity
GO:0003713 IMP transcription coactivator activity
GO:0003714 IDA transcription corepressor activity
GO:0005102 IDA receptor binding
GO:0005515 IPI protein binding
GO:0005634 IDA:IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006367 TAS transcription initiation from RNA polymerase II promoter
GO:0006468 IMP protein phosphorylation
GO:0007165 IDA signal transduction
GO:0008134 IPI transcription factor binding
GO:0008270 IEA zinc ion binding
GO:0008284 IMP positive regulation of cell proliferation
GO:0009986 IC cell surface
GO:0010467 TAS gene expression
GO:0019899 IPI enzyme binding
GO:0019904 IPI protein domain specific binding
GO:0030520 IDA intracellular estrogen receptor signaling pathway
GO:0030853 IDA negative regulation of granulocyte differentiation
GO:0031490 IDA chromatin DNA binding
GO:0032355 IDA response to estradiol
GO:0032526 IMP response to retinoic acid
GO:0032689 IDA negative regulation of interferon-gamma production
GO:0032720 IDA negative regulation of tumor necrosis factor production
GO:0032736 IDA positive regulation of interleukin-13 production
GO:0032753 IDA positive regulation of interleukin-4 production
GO:0032754 IDA positive regulation of interleukin-5 production
GO:0043277 IMP apoptotic cell clearance
GO:0043401 IEA steroid hormone mediated signaling pathway
GO:0043422 IPI protein kinase B binding
GO:0043565 IEA sequence-specific DNA binding
GO:0044323 IDA retinoic acid-responsive element binding
GO:0045630 IDA positive regulation of T-helper 2 cell differentiation
GO:0045787 IMP positive regulation of cell cycle
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046982 IDA protein heterodimerization activity
GO:0048384 IMP retinoic acid receptor signaling pathway
GO:0051018 IDA protein kinase A binding
GO:0051099 IMP positive regulation of binding
GO:0071300 IDA cellular response to retinoic acid
GO:0071391 IDA cellular response to estrogen stimulus

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000107475 Rara-002 protein_coding Mus_musculus 0 2351
ENSMUST00000107474 Rara-003 protein_coding Mus_musculus 0 2194
ENSMUST00000164748 Rara-201 protein_coding Mus_musculus 0 2193
ENSMUST00000068133 Rara-001 protein_coding Mus_musculus 0 2193
ENSMUST00000107473 Rara-004 protein_coding Mus_musculus 0 1714
ENSDART00000126022 rarab-201 protein_coding Danio_rerio 0 863
ENSDART00000044677 rarab-001 protein_coding Danio_rerio 0 835
ENSMUST00000063750 Rarb-201 protein_coding Mus_musculus 0 684

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