C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: retinoic acid receptor, alpha
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000068133 Rara-001 ENSMUSG00000037992 10090 + 11:98937718-98974942 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; MuscleENSMUST00000068133
Transcript ID Muscle
ENSMUST00000068133 0.319±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00098Y CIL_00098Y_0002 VISTA 11:98447152-99051430
CIL_0002GL CIL_0002GL_0002 CGP 11:98907801-98974942
CIL_00050G CIL_00050G_0002 CGP 11:98927818-98983016

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IGI negative regulation of transcription from RNA polymerase II promoter
GO:0000790 IEA nuclear chromatin
GO:0000900 IEA translation repressor activity, nucleic acid binding
GO:0000977 IDA RNA polymerase II regulatory region sequence-specific DNA binding
GO:0001012 IDA RNA polymerase II regulatory region DNA binding
GO:0001657 IMP ureteric bud development
GO:0001843 IGI neural tube closure
GO:0001889 IEA liver development
GO:0001972 IEA retinoic acid binding
GO:0002068 IGI glandular epithelial cell development
GO:0003148 IGI outflow tract septum morphogenesis
GO:0003417 IGI growth plate cartilage development
GO:0003677 IDA DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0003707 IEA steroid hormone receptor activity
GO:0003708 IDA retinoic acid receptor activity
GO:0003713 IEA transcription coactivator activity
GO:0003714 IEA transcription corepressor activity
GO:0004879 IDA ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0005102 IEA receptor binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0006468 IEA protein phosphorylation
GO:0007165 IEA signal transduction
GO:0007281 IMP germ cell development
GO:0007283 IMP spermatogenesis
GO:0007565 IEA female pregnancy
GO:0008134 IPI transcription factor binding
GO:0008144 IEA drug binding
GO:0008270 IEA zinc ion binding
GO:0008284 IGI positive regulation of cell proliferation
GO:0008285 IEA negative regulation of cell proliferation
GO:0008584 IEA male gonad development
GO:0010628 IMP positive regulation of gene expression
GO:0010629 IGI negative regulation of gene expression
GO:0014068 IEA positive regulation of phosphatidylinositol 3-kinase signaling
GO:0017148 IEA negative regulation of translation
GO:0019899 IEA enzyme binding
GO:0019904 IEA protein domain specific binding
GO:0030425 IDA dendrite
GO:0030520 IEA intracellular estrogen receptor signaling pathway
GO:0030850 IEA prostate gland development
GO:0030852 IMP regulation of granulocyte differentiation
GO:0030853 IEA negative regulation of granulocyte differentiation
GO:0031076 IGI embryonic camera-type eye development
GO:0031490 IEA chromatin DNA binding
GO:0031641 IEA regulation of myelination
GO:0032355 IEA response to estradiol
GO:0032526 IMP response to retinoic acid
GO:0032689 IEA negative regulation of interferon-gamma production
GO:0032720 IEA negative regulation of tumor necrosis factor production
GO:0032736 IEA positive regulation of interleukin-13 production
GO:0032753 IEA positive regulation of interleukin-4 production
GO:0032754 IEA positive regulation of interleukin-5 production
GO:0033189 IEA response to vitamin A
GO:0034097 IEA response to cytokine
GO:0035014 IEA phosphatidylinositol 3-kinase regulator activity
GO:0035264 IGI multicellular organism growth
GO:0042981 IEA regulation of apoptotic process
GO:0043005 IEA neuron projection
GO:0043025 IDA neuronal cell body
GO:0043066 IGI negative regulation of apoptotic process
GO:0043277 IEA apoptotic cell clearance
GO:0043401 IEA steroid hormone mediated signaling pathway
GO:0043422 IEA protein kinase B binding
GO:0043551 IEA regulation of phosphatidylinositol 3-kinase activity
GO:0043565 IDA sequence-specific DNA binding
GO:0044212 IMP transcription regulatory region DNA binding
GO:0044323 IEA retinoic acid-responsive element binding
GO:0045471 IEA response to ethanol
GO:0045596 IMP negative regulation of cell differentiation
GO:0045630 IEA positive regulation of T-helper 2 cell differentiation
GO:0045666 IEA positive regulation of neuron differentiation
GO:0045787 IEA positive regulation of cell cycle
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0045944 IGI positive regulation of transcription from RNA polymerase II promoter
GO:0045947 IDA negative regulation of translational initiation
GO:0046982 IEA protein heterodimerization activity
GO:0048027 IEA mRNA 5'-UTR binding
GO:0048167 IEA regulation of synaptic plasticity
GO:0048384 IEA retinoic acid receptor signaling pathway
GO:0048471 IEA perinuclear region of cytoplasm
GO:0051018 IEA protein kinase A binding
GO:0051099 IEA positive regulation of binding
GO:0051897 IEA positive regulation of protein kinase B signaling
GO:0055012 IMP ventricular cardiac muscle cell differentiation
GO:0060010 IMP Sertoli cell fate commitment
GO:0060173 IGI limb development
GO:0060324 IGI face development
GO:0060348 IGI bone development
GO:0060534 IMP trachea cartilage development
GO:0060591 IMP chondroblast differentiation
GO:0061037 IMP negative regulation of cartilage development
GO:0070374 IEA positive regulation of ERK1 and ERK2 cascade
GO:0071222 IDA cellular response to lipopolysaccharide
GO:0071300 IEA cellular response to retinoic acid
GO:0071391 IEA cellular response to estrogen stimulus

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000254066 RARA-001 protein_coding Homo_sapiens 0 2252
ENST00000330688 RARB-001 protein_coding Homo_sapiens 0 592
ENST00000383772 RARB-005 protein_coding Homo_sapiens 0 569
ENST00000394081 RARA-004 protein_coding Homo_sapiens 0 1773
ENST00000394086 RARA-003 protein_coding Homo_sapiens 0 1773
ENST00000394089 RARA-002 protein_coding Homo_sapiens 0 2193
ENST00000420042 RARA-006 processed_transcript Homo_sapiens 0 1245
ENST00000425707 RARA-007 protein_coding Homo_sapiens 0 1354
ENST00000437042 RARB-002 protein_coding Homo_sapiens 0 592
ENST00000458646 RARB-004 protein_coding Homo_sapiens 0 592
ENST00000462272 RARB-008 processed_transcript Homo_sapiens 0 335
ENST00000475125 RARA-005 protein_coding Homo_sapiens 0 1090
ENST00000479097 RARB-009 processed_transcript Homo_sapiens 2e-40 171
ENST00000480001 RARB-007 processed_transcript Homo_sapiens 0 335
ENST00000489694 RARB-006 processed_transcript Homo_sapiens 8e-17 92
ENST00000577646 RARA-008 protein_coding Homo_sapiens 0 510
ENST00000579727 RARA-010 processed_transcript Homo_sapiens 0 257
ENST00000617726 RARA-201 protein_coding Homo_sapiens 0 1748

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