C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: integrin-linked kinase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000396751 ILK-003 ENSG00000166333 9606 + 11:6603816-6610870 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; OvaryENST00000396751
Transcript ID Ovary
ENST00000396751 2.356±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001HZ CIL_0001HZ_0001 CGP 11:6595075-6610874
CIL_0003X8 CIL_0003X8_0001 CGP 11:6603708-6612667

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001558 IEA regulation of cell growth
GO:0001658 IEA branching involved in ureteric bud morphogenesis
GO:0001725 IEA stress fiber
GO:0001954 IEA positive regulation of cell-matrix adhesion
GO:0004672 IEA protein kinase activity
GO:0004674 IDA:IEA protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0004871 IEA signal transducer activity
GO:0005178 IEA integrin binding
GO:0005515 IPI:IEA protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0005886 IEA plasma membrane
GO:0005911 IEA cell-cell junction
GO:0005925 IDA focal adhesion
GO:0006468 IDA:IEA protein phosphorylation
GO:0006469 IEA negative regulation of protein kinase activity
GO:0007050 IEA cell cycle arrest
GO:0007160 TAS cell-matrix adhesion
GO:0007229 IDA integrin-mediated signaling pathway
GO:0007569 IEA cell aging
GO:0008283 NAS cell proliferation
GO:0008284 IEA positive regulation of cell proliferation
GO:0009966 IEA regulation of signal transduction
GO:0010667 IEA negative regulation of cardiac muscle cell apoptotic process
GO:0010761 IEA fibroblast migration
GO:0014044 IEA Schwann cell development
GO:0014912 IEA negative regulation of smooth muscle cell migration
GO:0016020 IDA membrane
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0017124 IEA SH3 domain binding
GO:0018105 IEA peptidyl-serine phosphorylation
GO:0019901 IPI protein kinase binding
GO:0021675 IEA nerve development
GO:0022011 IEA myelination in peripheral nervous system
GO:0030027 IEA lamellipodium
GO:0030030 IEA cell projection organization
GO:0030054 IDA cell junction
GO:0030335 IEA positive regulation of cell migration
GO:0030424 IEA axon
GO:0030513 IEA positive regulation of BMP signaling pathway
GO:0032288 IEA myelin assembly
GO:0032956 IEA regulation of actin cytoskeleton organization
GO:0034329 TAS cell junction assembly
GO:0034446 IMP substrate adhesion-dependent cell spreading
GO:0042327 IMP positive regulation of phosphorylation
GO:0043025 IEA neuronal cell body
GO:0043034 IEA costamere
GO:0043066 IEA negative regulation of apoptotic process
GO:0043195 IEA terminal bouton
GO:0043198 IEA dendritic shaft
GO:0043206 IEA extracellular fibril organization
GO:0043234 IEA protein complex
GO:0043406 IEA positive regulation of MAP kinase activity
GO:0043410 IEA positive regulation of MAPK cascade
GO:0043491 IEA protein kinase B signaling
GO:0043524 IEA negative regulation of neuron apoptotic process
GO:0045197 IEA establishment or maintenance of epithelial cell apical/basal polarity
GO:0045663 IEA positive regulation of myoblast differentiation
GO:0045669 IEA positive regulation of osteoblast differentiation
GO:0045773 IEA positive regulation of axon extension
GO:0045893 IMP positive regulation of transcription, DNA-templated
GO:0048662 IEA negative regulation of smooth muscle cell proliferation
GO:0048812 IEA neuron projection morphogenesis
GO:0050772 IEA positive regulation of axonogenesis
GO:0050775 IEA positive regulation of dendrite morphogenesis
GO:0051291 IEA protein heterooligomerization
GO:0051897 IEA positive regulation of protein kinase B signaling
GO:0070527 IMP platelet aggregation
GO:0090263 IMP positive regulation of canonical Wnt signaling pathway
GO:2000178 IEA negative regulation of neural precursor cell proliferation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000163389 Ilk-201 protein_coding Mus_musculus 0 2211
ENSMUST00000033182 Ilk-001 protein_coding Mus_musculus 0 2211
ENSMUST00000120029 Gm6263-001 processed_pseudogene Mus_musculus 0 1618
ENSMUST00000149695 Ilk-002 retained_intron Mus_musculus 0 985
ENSMUST00000154626 Ilk-005 retained_intron Mus_musculus 0 889
ENSMUST00000148971 Ilk-007 retained_intron Mus_musculus 0 885
ENSMUST00000130565 Ilk-012 retained_intron Mus_musculus 0 802
ENSMUST00000136687 Ilk-004 protein_coding Mus_musculus 0 798
ENSMUST00000138150 Ilk-010 processed_transcript Mus_musculus 0 715
ENSMUST00000127298 Ilk-008 protein_coding Mus_musculus 0 675
ENSMUST00000141116 Taf10-001 protein_coding Mus_musculus 0 516
ENSMUST00000145123 Ilk-006 retained_intron Mus_musculus 0 403
ENSMUST00000153557 Ilk-003 retained_intron Mus_musculus 0 272
ENSMUST00000152508 Ilk-011 retained_intron Mus_musculus 0 230
ENSMUST00000151108 Ilk-009 retained_intron Mus_musculus 0 222
ENSMUST00000098148 Rrp8-002 protein_coding Mus_musculus 8.00001e-42 176

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