C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: EPH receptor A4
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000409938 EPHA4-001 ENSG00000116106 9606 - 2:221425901-221574202 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000409938
Transcript ID Brain Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000409938 6.296±0.00 1.604±0.00 0.994±0.00 0.079±0.00 1.355±0.00 1.902±0.00 0.174±0.00 0.988±0.00 0.194±0.00 3.916±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006O4 CIL_0006O4_0001 CGP 2:219627327-221574202
CIL_0006XL CIL_0006XL_0001 CGP 2:221418027-222298996

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004672 IDA:IEA protein kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005003 IEA ephrin receptor activity
GO:0005004 ISS GPI-linked ephrin receptor activity
GO:0005005 ISS transmembrane-ephrin receptor activity
GO:0005515 IPI:IEA protein binding
GO:0005524 IEA ATP binding
GO:0005737 ISS cytoplasm
GO:0005887 ISS:IEA integral component of plasma membrane
GO:0006468 IEA protein phosphorylation
GO:0007155 IEA cell adhesion
GO:0007169 IEA transmembrane receptor protein tyrosine kinase signaling pathway
GO:0008045 ISS motor neuron axon guidance
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018108 IEA:IDA peptidyl-tyrosine phosphorylation
GO:0021957 ISS corticospinal tract morphogenesis
GO:0030054 IEA cell junction
GO:0030424 ISS axon
GO:0030425 ISS dendrite
GO:0031901 ISS early endosome membrane
GO:0032314 ISS regulation of Rac GTPase activity
GO:0032317 ISS regulation of Rap GTPase activity
GO:0042731 IPI PH domain binding
GO:0045211 IEA postsynaptic membrane
GO:0046777 IDA protein autophosphorylation
GO:0048013 IEA ephrin receptor signaling pathway
GO:0048681 ISS negative regulation of axon regeneration
GO:0048710 ISS regulation of astrocyte differentiation
GO:0050770 ISS regulation of axonogenesis
GO:0061001 ISS regulation of dendritic spine morphogenesis
GO:0097155 ISS fasciculation of sensory neuron axon
GO:0097156 ISS fasciculation of motor neuron axon
GO:0097161 IDA DH domain binding
GO:2001108 IDA positive regulation of Rho guanyl-nucleotide exchange factor activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000027451 Epha4-201 protein_coding Mus_musculus 0 4174
ENSMUST00000188797 Epha4-001 protein_coding Mus_musculus 0 4174
ENSMUST00000188952 Epha4-002 nonsense_mediated_decay Mus_musculus 0 4174
ENSMUST00000190149 Epha4-003 nonsense_mediated_decay Mus_musculus 0 3860
ENSMUST00000189934 Epha4-004 retained_intron Mus_musculus 0 2362
ENSMUST00000186930 Epha4-005 protein_coding Mus_musculus 0 562
ENSDART00000156185 ephb2a-201 protein_coding Danio_rerio 0 459
ENSDART00000148120 ephb2a-001 protein_coding Danio_rerio 0 459
ENSMUST00000187346 Epha4-006 protein_coding Mus_musculus 0 433
ENSDART00000050395 EPHB3 (2 of 2)-201 protein_coding Danio_rerio 0 348

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