C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: Eph receptor A4
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000027451 Epha4-201 ENSMUSG00000026235 10090 - 1:77367185-77515088 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverMuscleOvaryPlacentaTestisENSMUST00000027451
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Muscle Ovary Placenta Testis
ENSMUST00000027451 0.923±0.00 0.122±0.09 1.681±0.00 6.775±3.75 0.297±0.03 0.463±0.13 5.096±0.79 0.415±0.04 0.026±0.01 0.389±0.00 0.764±0.29 1.266±0.13 0.019±0.01

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006O4 CIL_0006O4_0002 CGP 1:75546266-77515088
CIL_0006XL CIL_0006XL_0002 CGP 1:77367185-78197134

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004672 ISS protein kinase activity
GO:0005004 IMP GPI-linked ephrin receptor activity
GO:0005005 IDA transmembrane-ephrin receptor activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005737 ISS cytoplasm
GO:0005741 IEA mitochondrial outer membrane
GO:0005783 IEA endoplasmic reticulum
GO:0005794 IEA Golgi apparatus
GO:0005886 IEA plasma membrane
GO:0005887 IDA integral component of plasma membrane
GO:0007155 IEA cell adhesion
GO:0007411 IMP axon guidance
GO:0007628 IMP adult walking behavior
GO:0008045 IMP motor neuron axon guidance
GO:0008347 IEA glial cell migration
GO:0009986 IEA cell surface
GO:0014069 IEA postsynaptic density
GO:0018108 ISS peptidyl-tyrosine phosphorylation
GO:0021957 IMP corticospinal tract morphogenesis
GO:0030054 IEA cell junction
GO:0030175 IEA filopodium
GO:0030424 IDA axon
GO:0030425 IDA dendrite
GO:0031594 IEA neuromuscular junction
GO:0031901 IDA early endosome membrane
GO:0032314 IDA regulation of Rac GTPase activity
GO:0032317 IMP regulation of Rap GTPase activity
GO:0032319 IEA regulation of Rho GTPase activity
GO:0042731 IEA PH domain binding
GO:0042802 IPI identical protein binding
GO:0042995 IEA cell projection
GO:0043197 IEA dendritic spine
GO:0043204 IEA perikaryon
GO:0043507 IDA positive regulation of JUN kinase activity
GO:0043679 IEA axon terminus
GO:0044295 IEA axonal growth cone
GO:0044297 IEA cell body
GO:0045211 IEA postsynaptic membrane
GO:0046777 ISS protein autophosphorylation
GO:0046875 IEA ephrin receptor binding
GO:0048013 IEA ephrin receptor signaling pathway
GO:0048681 IMP negative regulation of axon regeneration
GO:0048710 IMP regulation of astrocyte differentiation
GO:0050770 IMP regulation of axonogenesis
GO:0050775 IEA positive regulation of dendrite morphogenesis
GO:0061001 IMP regulation of dendritic spine morphogenesis
GO:0097155 IMP fasciculation of sensory neuron axon
GO:0097156 IMP fasciculation of motor neuron axon
GO:0097161 ISS DH domain binding
GO:2001108 ISS positive regulation of Rho guanyl-nucleotide exchange factor activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000098632 epha4a-201 protein_coding Danio_rerio 0 1500
ENSDART00000004338 epha4l-001 protein_coding Danio_rerio 0 996
ENSDART00000006787 epha3-001 protein_coding Danio_rerio 0 507
ENSDART00000050395 EPHB3 (2 of 2)-201 protein_coding Danio_rerio 0 411
ENSDART00000149895 epha4a-001 protein_coding Danio_rerio 0 331
ENST00000281821 EPHA4-201 protein_coding Homo_sapiens 0 4946
ENST00000409854 EPHA4-003 protein_coding Homo_sapiens 0 3847
ENST00000409938 EPHA4-001 protein_coding Homo_sapiens 0 4174
ENST00000415749 EPHA4-013 nonsense_mediated_decay Homo_sapiens 0 523
ENST00000419964 EPHA4-005 protein_coding Homo_sapiens 0 630
ENST00000424339 EPHA4-009 nonsense_mediated_decay Homo_sapiens 0 499
ENST00000434266 EPHA4-004 protein_coding Homo_sapiens 0 455
ENST00000441679 EPHA4-006 protein_coding Homo_sapiens 0 734
ENST00000443796 EPHA4-012 protein_coding Homo_sapiens 0 562
ENST00000463446 EPHA4-007 retained_intron Homo_sapiens 0 571
ENST00000469354 EPHA4-014 processed_transcript Homo_sapiens 0 1441
ENST00000495693 EPHA4-008 retained_intron Homo_sapiens 0 291
ENST00000541600 EPHA4-002 protein_coding Homo_sapiens 0 713

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