C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: integrin-linked kinase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000420936 ILK-002 ENSG00000166333 9606 + 11:6603758-6610833 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartLiverLungOvaryPlacentaTestisENST00000420936
Transcript ID Adipose Adrenal Brain Breast Colon Heart Liver Lung Ovary Placenta Testis
ENST00000420936 19.763±0.00 26.955±0.00 2.769±0.00 30.178±0.00 28.885±24.20 13.951±11.50 7.657±0.00 2.939±0.00 66.023±0.00 58.122±28.91 30.022±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001HZ CIL_0001HZ_0001 CGP 11:6595075-6610874
CIL_0003X8 CIL_0003X8_0001 CGP 11:6603708-6612667

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004672 IEA protein kinase activity
GO:0004674 IDA:IEA protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI:IEA protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0005886 IEA plasma membrane
GO:0005925 IDA focal adhesion
GO:0006468 IDA:IEA protein phosphorylation
GO:0007160 TAS cell-matrix adhesion
GO:0007229 IDA integrin-mediated signaling pathway
GO:0008283 NAS cell proliferation
GO:0009966 IEA regulation of signal transduction
GO:0016020 IDA membrane
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0019901 IPI protein kinase binding
GO:0030054 IDA cell junction
GO:0034329 TAS cell junction assembly
GO:0034446 IMP substrate adhesion-dependent cell spreading
GO:0042327 IMP positive regulation of phosphorylation
GO:0045893 IMP positive regulation of transcription, DNA-templated
GO:0070527 IMP platelet aggregation
GO:0090263 IMP positive regulation of canonical Wnt signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000033182 Ilk-001 protein_coding Mus_musculus 0 2224
ENSMUST00000163389 Ilk-201 protein_coding Mus_musculus 0 2143
ENSMUST00000120029 Gm6263-001 processed_pseudogene Mus_musculus 0 1618
ENSMUST00000149695 Ilk-002 retained_intron Mus_musculus 0 924
ENSMUST00000154626 Ilk-005 retained_intron Mus_musculus 0 889
ENSMUST00000148971 Ilk-007 retained_intron Mus_musculus 0 885
ENSMUST00000130565 Ilk-012 retained_intron Mus_musculus 0 802
ENSMUST00000136687 Ilk-004 protein_coding Mus_musculus 0 798
ENSMUST00000138150 Ilk-010 processed_transcript Mus_musculus 0 715
ENSMUST00000127298 Ilk-008 protein_coding Mus_musculus 0 675
ENSMUST00000141116 Taf10-001 protein_coding Mus_musculus 0 448
ENSMUST00000145123 Ilk-006 retained_intron Mus_musculus 0 403
ENSMUST00000153557 Ilk-003 retained_intron Mus_musculus 0 272
ENSMUST00000152508 Ilk-011 retained_intron Mus_musculus 0 230
ENSMUST00000151108 Ilk-009 retained_intron Mus_musculus 0 222
ENSMUST00000098148 Rrp8-002 protein_coding Mus_musculus 6.00036e-42 176

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