C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: glutamate receptor, ionotropic, kainate 2 (beta 2)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000105487 Grik2-001 ENSMUSG00000056073 10090 - 10:49099460-49788766 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENSMUST00000105487
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENSMUST00000105487 0.015±0.00 0.240±0.15 0.050±0.00 8.180±0.31 0.084±0.01 0.160±0.00 0.052±0.02 0.046±0.00 0.030±0.02 0.117±0.08 0.018±0.00 0.094±0.04 0.007±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001662 IMP behavioral fear response
GO:0004970 IMP ionotropic glutamate receptor activity
GO:0005234 IBA extracellular-glutamate-gated ion channel activity
GO:0005515 IPI protein binding
GO:0005887 IEA integral component of plasma membrane
GO:0006874 IMP cellular calcium ion homeostasis
GO:0006886 IDA intracellular protein transport
GO:0007165 IEA signal transduction
GO:0007268 IGI synaptic transmission
GO:0008066 IEA glutamate receptor activity
GO:0008328 IC ionotropic glutamate receptor complex
GO:0014069 IDA postsynaptic density
GO:0015277 IMP kainate selective glutamate receptor activity
GO:0016020 IDA membrane
GO:0019228 IMP neuronal action potential
GO:0030054 IEA cell junction
GO:0030165 IEA PDZ domain binding
GO:0030424 IEA axon
GO:0030425 IBA dendrite
GO:0031624 IEA ubiquitin conjugating enzyme binding
GO:0031625 IEA ubiquitin protein ligase binding
GO:0032839 IEA dendrite cytoplasm
GO:0032983 IPI kainate selective glutamate receptor complex
GO:0034220 IEA ion transmembrane transport
GO:0035235 IEA ionotropic glutamate receptor signaling pathway
GO:0035249 IMP synaptic transmission, glutamatergic
GO:0042391 IMP regulation of membrane potential
GO:0042734 IDA presynaptic membrane
GO:0042802 IEA identical protein binding
GO:0042803 IEA protein homodimerization activity
GO:0043025 IDA neuronal cell body
GO:0043113 IEA receptor clustering
GO:0043195 IEA terminal bouton
GO:0043204 IEA perikaryon
GO:0043524 IGI negative regulation of neuron apoptotic process
GO:0043525 IEA positive regulation of neuron apoptotic process
GO:0045202 TAS synapse
GO:0045211 IDA postsynaptic membrane
GO:0046328 IEA regulation of JNK cascade
GO:0048169 IMP regulation of long-term neuronal synaptic plasticity
GO:0048172 IMP regulation of short-term neuronal synaptic plasticity
GO:0050804 IEA regulation of synaptic transmission
GO:0050806 IEA positive regulation of synaptic transmission
GO:0051402 IEA neuron apoptotic process
GO:0051967 IGI negative regulation of synaptic transmission, glutamatergic
GO:0060079 IMP regulation of excitatory postsynaptic membrane potential
GO:0060080 IGI regulation of inhibitory postsynaptic membrane potential

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000109264 GRIK2 (1 of 2)-201 protein_coding Danio_rerio 0 1578
ENST00000309434 GRIK1-201 protein_coding Homo_sapiens 0 815
ENST00000318991 GRIK2-201 protein_coding Homo_sapiens 0 3494
ENST00000327783 GRIK1-004 protein_coding Homo_sapiens 0 815
ENST00000358361 GRIK2-008 protein_coding Homo_sapiens 0 1550
ENST00000369134 GRIK2-202 protein_coding Homo_sapiens 0 4311
ENST00000369137 GRIK2-203 protein_coding Homo_sapiens 0 3491
ENST00000369138 GRIK2-003 protein_coding Homo_sapiens 0 3934
ENST00000389124 GRIK1-005 protein_coding Homo_sapiens 0 815
ENST00000389125 GRIK1-001 protein_coding Homo_sapiens 0 1173
ENST00000399907 GRIK1-002 protein_coding Homo_sapiens 0 815
ENST00000399909 GRIK1-008 protein_coding Homo_sapiens 0 1171
ENST00000399913 GRIK1-006 protein_coding Homo_sapiens 0 817
ENST00000399914 GRIK1-003 protein_coding Homo_sapiens 0 1171
ENST00000413795 GRIK2-002 protein_coding Homo_sapiens 0 3930
ENST00000421544 GRIK2-001 protein_coding Homo_sapiens 0 4750
ENST00000436862 GRIK2-005 protein_coding Homo_sapiens 0 850
ENST00000455610 GRIK2-004 protein_coding Homo_sapiens 0 588
ENST00000487161 GRIK2-006 retained_intron Homo_sapiens 0 601
ENST00000487395 GRIK2-007 retained_intron Homo_sapiens 0 350
ENST00000535441 GRIK1-202 protein_coding Homo_sapiens 0 1173

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