C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: methyl-CpG binding domain protein 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000434436 MBD3-001 ENSG00000071655 9606 - 19:1576678-1592708 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonKidneyLiverLungMuscleOvaryPlacentaTestisENST00000434436
Transcript ID Adipose Adrenal Brain Breast Colon Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000434436 21.704±0.00 29.709±0.00 11.603±8.90 46.506±0.00 25.443±0.00 12.354±10.67 12.139±10.93 19.371±0.00 11.262±0.00 31.031±22.36 42.988±17.15 29.017±9.79

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003YO CIL_0003YO_0001 CGP 19:1554669-1592801
CIL_0003Z8 CIL_0003Z8_0001 CGP 19:1573596-1605445

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0000785 IEA chromatin
GO:0000790 IDA nuclear chromatin
GO:0000792 IEA heterochromatin
GO:0000978 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000980 IDA RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0001701 IEA in utero embryonic development
GO:0003677 TAS:IEA DNA binding
GO:0003682 IEA chromatin binding
GO:0005488 IEA binding
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0006346 IEA methylation-dependent chromatin silencing
GO:0006351 IEA transcription, DNA-templated
GO:0008327 IDA methyl-CpG binding
GO:0009888 IEA tissue development
GO:0016573 IEA histone acetylation
GO:0016581 NAS NuRD complex
GO:0031492 IDA nucleosomal DNA binding
GO:0043044 IDA ATP-dependent chromatin remodeling
GO:0043234 IDA protein complex

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000092295 Mbd3-001 protein_coding Mus_musculus 0 1064
ENSMUST00000105347 Mbd3-006 protein_coding Mus_musculus 0 846
ENSMUST00000105349 Mbd3-002 protein_coding Mus_musculus 0 846
ENSMUST00000105348 Mbd3-003 protein_coding Mus_musculus 0 645
ENSMUST00000142997 Mbd3-004 protein_coding Mus_musculus 0 603
ENSMUST00000125618 Mbd3-005 processed_transcript Mus_musculus 0 453

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