C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: cyclin-dependent kinase 12
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000447079 CDK12-001 ENSG00000167258 9606 + 17:39462039-39535146 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000447079
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000447079 1.096±0.00 1.019±0.00 0.914±0.00 0.812±0.32 0.984±0.23 1.857±0.00 0.834±0.46 1.816±0.40 1.306±0.15 2.254±0.08 0.191±0.00 2.540±0.87 1.402±0.46 3.587±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008SN CIL_0008SN_0001 VISTA 17:39110111-39710718
CIL_00080Z CIL_00080Z_0001 VISTA 17:39318232-39918735
CIL_00098W CIL_00098W_0001 VISTA 17:39359510-39962707
CIL_0007WH CIL_0007WH_0001 VISTA 17:39374871-39978277
CIL_0007D3 CIL_0007D3_0001 CGP 17:39404285-39564907
CIL_0007D4 CIL_0007D4_0001 CGP 17:39461511-39609777

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002944 IPI cyclin K-CDK12 complex
GO:0004672 IDA:IEA protein kinase activity
GO:0004693 IEA cyclin-dependent protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005730 IDA nucleolus
GO:0006397 IEA mRNA processing
GO:0006468 IEA protein phosphorylation
GO:0008353 IMP RNA polymerase II carboxy-terminal domain kinase activity
GO:0008380 ISS RNA splicing
GO:0016607 IDA nuclear speck
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0019908 ISS nuclear cyclin-dependent protein kinase holoenzyme complex
GO:0030332 IPI cyclin binding
GO:0043405 IMP regulation of MAP kinase activity
GO:0046777 IDA protein autophosphorylation
GO:0051726 IEA regulation of cell cycle
GO:0070816 IMP phosphorylation of RNA polymerase II C-terminal domain

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000107538 Cdk12-001 protein_coding Mus_musculus 0 5928
ENSMUST00000107539 Cdk12-005 protein_coding Mus_musculus 0 5716
ENSMUST00000003203 Cdk12-002 protein_coding Mus_musculus 0 4723
ENSMUST00000147441 Cdk12-006 processed_transcript Mus_musculus 0 1376
ENSMUST00000119645 Gm14208-001 processed_pseudogene Mus_musculus 0 739
ENSDART00000114544 cdk13-001 protein_coding Danio_rerio 0 551
ENSMUST00000145113 Cdk12-003 processed_transcript Mus_musculus 0 451

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