C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000449767 OGDH-002 ENSG00000105953 9606 + 7:44606591-44708328 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonOvaryTestisENST00000449767
Transcript ID Adipose Bladder Brain Breast Colon Ovary Testis
ENST00000449767 4.435±0.00 4.674±0.00 11.546±0.00 8.406±0.00 3.356±0.00 4.348±0.00 6.442±0.42

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000J7 CIL_0000J7_0001 CGP 7:44577894-44709066
CIL_0000J8 CIL_0000J8_0001 CGP 7:44606572-44769881

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004591 ISS:IEA oxoglutarate dehydrogenase (succinyl-transferring) activity
GO:0005739 IDA mitochondrion
GO:0005759 TAS mitochondrial matrix
GO:0006091 ISS generation of precursor metabolites and energy
GO:0006096 IEA glycolytic process
GO:0006099 TAS:IEA tricarboxylic acid cycle
GO:0006554 TAS lysine catabolic process
GO:0008152 IEA metabolic process
GO:0016624 IEA oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GO:0030976 IEA thiamine pyrophosphate binding
GO:0031966 ISS mitochondrial membrane
GO:0034641 TAS cellular nitrogen compound metabolic process
GO:0044237 TAS cellular metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0046872 IEA metal ion binding
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000081894 Ogdh-003 protein_coding Mus_musculus 0 3940
ENSMUST00000003461 Ogdh-001 protein_coding Mus_musculus 0 3771
ENSMUST00000101554 Ogdh-004 protein_coding Mus_musculus 0 3701
ENSMUST00000093350 Ogdh-002 protein_coding Mus_musculus 0 3188
ENSDART00000013485 ogdhb-201 protein_coding Danio_rerio 0 1666
ENSDART00000139214 ogdhb-001 protein_coding Danio_rerio 0 1666
ENSMUST00000140765 Ogdh-005 protein_coding Mus_musculus 0 523
ENSMUST00000125929 Ogdh-008 retained_intron Mus_musculus 0 399
ENSMUST00000135124 Ogdh-006 protein_coding Mus_musculus 0 381

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