C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: transforming growth factor, beta receptor III
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000465892 TGFBR3-002 ENSG00000069702 9606 - 1:91683729-91886109 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryENST00000465892
Transcript ID Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary
ENST00000465892 7.189±0.00 0.611±0.00 4.172±0.00 3.487±0.00 1.297±0.00 1.345±0.00 16.486±0.00 7.240±0.00 2.149±0.00 7.283±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00069I CIL_00069I_0001 CGP 1:91500893-91906335
CIL_0008DI CIL_0008DI_0001 VISTA 1:91505983-92108430
CIL_0008YV CIL_0008YV_0001 VISTA 1:91545179-92146674
CIL_0005ZR CIL_0005ZR_0001 CGP 1:91680343-92014426

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001837 IDA epithelial to mesenchymal transition
GO:0001889 ISS liver development
GO:0003007 ISS heart morphogenesis
GO:0005024 IDA transforming growth factor beta-activated receptor activity
GO:0005114 IDA type II transforming growth factor beta receptor binding
GO:0005160 ISS transforming growth factor beta receptor binding
GO:0005515 IPI protein binding
GO:0005539 ISS glycosaminoglycan binding
GO:0005615 IDA extracellular space
GO:0005887 ISS integral component of plasma membrane
GO:0006955 IMP immune response
GO:0007179 IMP transforming growth factor beta receptor signaling pathway
GO:0008201 ISS heparin binding
GO:0009897 IDA external side of plasma membrane
GO:0009986 ISS cell surface
GO:0015026 IDA coreceptor activity
GO:0016049 ISS cell growth
GO:0016477 ISS cell migration
GO:0030165 ISS PDZ domain binding
GO:0030509 IDA BMP signaling pathway
GO:0032354 IDA response to follicle-stimulating hormone
GO:0034673 IDA inhibin-betaglycan-ActRII complex
GO:0034695 IDA response to prostaglandin E
GO:0034699 IDA response to luteinizing hormone
GO:0035556 IMP intracellular signal transduction
GO:0046332 IMP SMAD binding
GO:0050431 IDA transforming growth factor beta binding
GO:0050680 ISS negative regulation of epithelial cell proliferation
GO:0051271 IDA negative regulation of cellular component movement
GO:0055010 ISS ventricular cardiac muscle tissue morphogenesis
GO:0060021 ISS palate development
GO:0060038 ISS cardiac muscle cell proliferation
GO:0060216 ISS definitive hemopoiesis
GO:0060317 IDA cardiac epithelial to mesenchymal transition
GO:0060318 ISS definitive erythrocyte differentiation
GO:0060347 ISS heart trabecula formation
GO:0060389 IMP pathway-restricted SMAD protein phosphorylation
GO:0070062 IDA extracellular vesicular exosome
GO:0070123 IDA transforming growth factor beta receptor activity, type III

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000031224 Tgfbr3-001 protein_coding Mus_musculus 0 2473
ENSMUST00000138469 Tgfbr3-003 processed_transcript Mus_musculus 0 2255
ENSMUST00000146591 Tgfbr3-002 retained_intron Mus_musculus 0 918
ENSMUST00000136882 Tgfbr3-004 protein_coding Mus_musculus 0 409

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