C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: amyloid beta (A4) precursor protein-binding, family B, member 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000508593 APBB2-003 ENSG00000163697 9606 - 4:40815324-41214532 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainBreastColonHeartKidneyLiverLungOvaryPlacentaENST00000508593
Transcript ID Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta
ENST00000508593 3.941±0.00 2.552±0.00 3.308±0.00 1.439±0.24 2.108±0.00 6.198±0.00 4.141±0.00 3.444±2.79 2.366±0.44

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00038T CIL_00038T_0001 CGP 4:40749897-41216714
CIL_00038S CIL_00038S_0001 CGP 4:40810027-41268455

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001540 ISS beta-amyloid binding
GO:0001764 IEA neuron migration
GO:0005515 IPI:IEA protein binding
GO:0005634 ISS nucleus
GO:0005737 IEA cytoplasm
GO:0006355 ISS regulation of transcription, DNA-templated
GO:0007050 ISS cell cycle arrest
GO:0007411 IEA axon guidance
GO:0008134 ISS transcription factor binding
GO:0016020 NAS membrane
GO:0030027 ISS lamellipodium
GO:0030198 IEA extracellular matrix organization
GO:0030308 ISS negative regulation of cell growth
GO:0030426 ISS growth cone
GO:0035556 NAS intracellular signal transduction
GO:0043065 IEA positive regulation of apoptotic process
GO:0043066 IEA negative regulation of apoptotic process
GO:0045202 ISS synapse

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000162349 Apbb2-004 protein_coding Mus_musculus 0 3234
ENSMUST00000159786 Apbb2-001 protein_coding Mus_musculus 0 3232
ENSMUST00000087256 Apbb2-201 protein_coding Mus_musculus 0 3212
ENSMUST00000160870 Apbb2-007 protein_coding Mus_musculus 0 1799
ENSMUST00000159512 Apbb2-003 protein_coding Mus_musculus 0 1796
ENSMUST00000162366 Apbb2-008 protein_coding Mus_musculus 0 1775
ENSMUST00000160185 Apbb2-006 retained_intron Mus_musculus 0 1347
ENSMUST00000162401 Apbb2-005 retained_intron Mus_musculus 0 1327
ENSMUST00000160775 Apbb2-018 processed_transcript Mus_musculus 0 1245
ENSMUST00000162955 Apbb2-002 processed_transcript Mus_musculus 0 1242
ENSMUST00000160063 Apbb2-017 protein_coding Mus_musculus 0 1013
ENSMUST00000161771 Apbb2-019 processed_transcript Mus_musculus 0 717
ENSMUST00000162382 Apbb2-014 protein_coding Mus_musculus 0 492
ENSMUST00000161879 Apbb2-016 protein_coding Mus_musculus 0 468
ENSMUST00000160103 Apbb2-011 protein_coding Mus_musculus 0 444
ENSMUST00000162994 Apbb2-009 protein_coding Mus_musculus 0 200
ENSMUST00000160054 Apbb2-020 retained_intron Mus_musculus 3.99931e-42 178
ENSMUST00000159357 Apbb2-015 protein_coding Mus_musculus 8e-34 150
ENSMUST00000161716 Apbb2-012 protein_coding Mus_musculus 5e-31 141

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