C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: dicer 1, ribonuclease type III
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000527414 DICER1-006 ENSG00000100697 9606 - 14:95090321-95136810 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryTestisENST00000527414
Transcript ID Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Testis
ENST00000527414 2.883±0.00 3.891±0.00 7.261±0.00 2.667±0.00 0.679±0.00 3.672±0.00 6.069±0.00 8.219±0.00 2.176±0.00 2.747±1.06 6.545±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00019X CIL_00019X_0002 CGP 14:94768216-95158010
CIL_00085I CIL_00085I_0001 VISTA 14:95070077-95673144
CIL_0003QP CIL_0003QP_0001 CGP 14:95086228-95319906

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 ISS negative regulation of transcription from RNA polymerase II promoter
GO:0003676 IEA nucleic acid binding
GO:0003677 IEA DNA binding
GO:0003723 IEA RNA binding
GO:0003725 IDA double-stranded RNA binding
GO:0004386 IEA helicase activity
GO:0004525 IDA:IEA ribonuclease III activity
GO:0005515 IPI:IEA protein binding
GO:0005524 IEA ATP binding
GO:0005829 TAS cytosol
GO:0006396 IEA RNA processing
GO:0010467 TAS gene expression
GO:0010626 ISS negative regulation of Schwann cell proliferation
GO:0014040 ISS positive regulation of Schwann cell differentiation
GO:0016442 IDA RISC complex
GO:0016787 IEA hydrolase activity
GO:0016891 IEA endoribonuclease activity, producing 5'-phosphomonoesters
GO:0021675 ISS nerve development
GO:0030422 IDA production of siRNA involved in RNA interference
GO:0030423 IMP targeting of mRNA for destruction involved in RNA interference
GO:0031054 IDA pre-miRNA processing
GO:0031643 ISS positive regulation of myelination
GO:0032290 ISS peripheral nervous system myelin formation
GO:0035196 ISS production of miRNAs involved in gene silencing by miRNA
GO:0046872 IEA metal ion binding
GO:0048812 ISS neuron projection morphogenesis
GO:0090501 IDA RNA phosphodiester bond hydrolysis
GO:0090502 IEA RNA phosphodiester bond hydrolysis, endonucleolytic

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000041987 Dicer1-201 protein_coding Mus_musculus 0 7232
ENSDART00000109826 dicer1-201 protein_coding Danio_rerio 0 606
ENSDART00000045881 dicer1-001 protein_coding Danio_rerio 0 606

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