C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info

Description: mesencephalic astrocyte-derived neurotrophic factor
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000528157 MANF-001 ENSG00000145050 9606 + 3:51385047-51389397 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000528157
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000528157 20.560±0.00 22.691±0.00 1.630±0.00 6.078±2.65 13.306±1.78 28.348±22.91 6.204±3.86 38.362±33.57 25.610±21.68 20.933±18.16 2.475±2.12 24.620±17.10 35.926±7.12 34.612±14.96

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003FL CIL_0003FL_0002 CGP 3:50675241-51389397
CIL_0005MV CIL_0005MV_0002 CGP 3:51385047-51397908

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002014 IEA vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure
GO:0005615 IEA extracellular space
GO:0005634 IDA nucleus
GO:0005783 IEA endoplasmic reticulum
GO:0006986 IEA response to unfolded protein
GO:0008083 IEA growth factor activity
GO:0008150 ND biological_process
GO:0044822 IDA poly(A) RNA binding
GO:0048471 IEA perinuclear region of cytoplasm

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000159283 Manf-001 protein_coding Mus_musculus 0 876
ENSMUST00000069036 Manf-002 protein_coding Mus_musculus 0 763
ENSMUST00000160978 Manf-004 protein_coding Mus_musculus 0 490
ENSMUST00000159620 Manf-007 protein_coding Mus_musculus 0 448
ENSMUST00000160503 Manf-005 protein_coding Mus_musculus 0 446
ENSMUST00000162801 Manf-003 retained_intron Mus_musculus 0 320

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