C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: vitamin D (1,25- dihydroxyvitamin D3) receptor
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000549336 VDR-004 ENSG00000111424 9606 - 12:47841537-47905022 protein_coding

Homo sapiens EnsemblGRCh38

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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonKidneyOvaryPlacentaTestisENST00000549336
Transcript ID Adipose Bladder Brain Breast Colon Kidney Ovary Placenta Testis
ENST00000549336 1.377±0.00 0.875±0.00 0.068±0.00 2.093±0.00 2.184±0.03 1.401±1.39 0.889±0.52 1.157±0.10 0.526±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003DI CIL_0003DI_0002 CGP 12:47782722-47943048
CIL_0005YK CIL_0005YK_0001 CGP 12:47841537-47968878

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000902 IMP cell morphogenesis
GO:0003677 IDA DNA binding
GO:0003700 IDA:IEA sequence-specific DNA binding transcription factor activity
GO:0003707 IEA steroid hormone receptor activity
GO:0005515 IPI protein binding
GO:0005634 IEA:IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006367 TAS transcription initiation from RNA polymerase II promoter
GO:0007165 TAS signal transduction
GO:0008270 IEA zinc ion binding
GO:0008285 IDA negative regulation of cell proliferation
GO:0008434 IEA:IDA calcitriol receptor activity
GO:0010467 TAS gene expression
GO:0010628 IMP positive regulation of gene expression
GO:0010839 IMP negative regulation of keratinocyte proliferation
GO:0010980 IDA positive regulation of vitamin D 24-hydroxylase activity
GO:0038183 IDA bile acid signaling pathway
GO:0038186 IDA lithocholic acid receptor activity
GO:0043401 IEA steroid hormone mediated signaling pathway
GO:0043565 IEA sequence-specific DNA binding
GO:0045618 IMP positive regulation of keratinocyte differentiation
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0046697 IEP decidualization
GO:0046965 IPI retinoid X receptor binding
GO:0060558 ISS regulation of calcidiol 1-monooxygenase activity
GO:0070561 IEA:IDA vitamin D receptor signaling pathway
GO:0070644 IDA vitamin D response element binding
GO:1902098 IDA calcitriol binding
GO:1902121 IDA lithocholic acid binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000023119 Vdr-001 protein_coding Mus_musculus 0 1493
ENSMUST00000126568 Vdr-002 protein_coding Mus_musculus 0 350
ENSMUST00000173104 Vdr-006 protein_coding Mus_musculus 0 261
ENSMUST00000174633 Vdr-004 protein_coding Mus_musculus 8e-30 137
ENSMUST00000173611 Vdr-005 protein_coding Mus_musculus 2e-25 122
ENSMUST00000173269 Neu1-002 retained_intron Mus_musculus 0.0000001 64

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