C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: synaptotagmin I
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000552744 SYT1-005 ENSG00000067715 9606 + 12:79045631-79450294 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; KidneyOvaryENST00000552744
Transcript ID Kidney Ovary
ENST00000552744 0.380±0.00 0.363±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002BE CIL_0002BE_0002 CGP 12:78863993-79691097

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000149 ISS SNARE binding
GO:0005215 IEA transporter activity
GO:0005513 TAS detection of calcium ion
GO:0005515 IPI:IEA protein binding
GO:0005544 ISS calcium-dependent phospholipid binding
GO:0005545 TAS 1-phosphatidylinositol binding
GO:0005886 TAS plasma membrane
GO:0007268 TAS synaptic transmission
GO:0007269 TAS neurotransmitter secretion
GO:0008021 TAS synaptic vesicle
GO:0014047 TAS glutamate secretion
GO:0016021 IEA integral component of membrane
GO:0017075 ISS syntaxin-1 binding
GO:0017157 TAS regulation of exocytosis
GO:0030054 IEA cell junction
GO:0030666 TAS endocytic vesicle membrane
GO:0043005 ISS neuron projection
GO:0048791 ISS calcium ion-dependent exocytosis of neurotransmitter
GO:0050750 IDA low-density lipoprotein particle receptor binding
GO:0050806 ISS positive regulation of synaptic transmission
GO:0051260 TAS protein homooligomerization
GO:0051966 ISS regulation of synaptic transmission, glutamatergic
GO:0060201 TAS clathrin-sculpted acetylcholine transport vesicle membrane
GO:0060203 TAS clathrin-sculpted glutamate transport vesicle membrane
GO:0061202 TAS clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane
GO:0070083 TAS clathrin-sculpted monoamine transport vesicle membrane
GO:1903305 ISS regulation of regulated secretory pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000064054 Syt1-006 protein_coding Mus_musculus 0 2948
ENSMUST00000105276 Syt1-001 protein_coding Mus_musculus 0 2948
ENSDART00000041861 syt1a-001 protein_coding Danio_rerio 0 665
ENSDART00000023562 SYT2 (2 of 4)-201 protein_coding Danio_rerio 0 412

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