C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: CCR4-NOT transcription complex, subunit 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000569240 CNOT1-003 ENSG00000125107 9606 - 16:58520695-58629834 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000569240
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000569240 5.958±0.00 5.977±0.00 4.610±0.00 6.435±0.62 8.081±0.47 5.805±2.68 6.702±1.18 5.750±2.02 8.630±0.76 8.767±4.28 6.965±1.71 8.590±2.36 36.994±10.24

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004IY CIL_0004IY_0001 CGP 16:58462846-58521181
CIL_0004IZ CIL_0004IZ_0001 CGP 16:58515479-58629886

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000288 TAS nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0000289 TAS nuclear-transcribed mRNA poly(A) tail shortening
GO:0000932 ISS cytoplasmic mRNA processing body
GO:0004535 IDA poly(A)-specific ribonuclease activity
GO:0005488 IEA binding
GO:0005515 IPI protein binding
GO:0005615 IDA extracellular space
GO:0005634 IDA nucleus
GO:0005778 IDA peroxisomal membrane
GO:0005829 TAS cytosol
GO:0006351 IEA transcription, DNA-templated
GO:0006417 IEA regulation of translation
GO:0010467 TAS gene expression
GO:0010606 IDA positive regulation of cytoplasmic mRNA processing body assembly
GO:0016020 IDA membrane
GO:0016070 TAS RNA metabolic process
GO:0016071 TAS mRNA metabolic process
GO:0030014 IDA CCR4-NOT complex
GO:0030331 IDA estrogen receptor binding
GO:0031047 IEA gene silencing by RNA
GO:0033147 IDA negative regulation of intracellular estrogen receptor signaling pathway
GO:0042974 IDA retinoic acid receptor binding
GO:0044822 IDA poly(A) RNA binding
GO:0048387 IDA negative regulation of retinoic acid receptor signaling pathway
GO:0060213 IMP positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
GO:0090503 IDA RNA phosphodiester bond hydrolysis, exonucleolytic
GO:1900153 IMP positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:2000036 IMP regulation of stem cell maintenance

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000098473 Cnot1-202 protein_coding Mus_musculus 0 10690
ENSMUST00000068452 Cnot1-201 protein_coding Mus_musculus 0 10260
ENSMUST00000185787 RP23-341D24.1-001 processed_pseudogene Mus_musculus 0 3153
ENSDART00000125459 cnot1-001 protein_coding Danio_rerio 0 3046
ENSDART00000017536 cnot1-201 protein_coding Danio_rerio 0 3037
ENSMUST00000109467 Gm6158-201 processed_pseudogene Mus_musculus 0 760

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